Results 201 to 210 of about 63,566 (275)

Plinia cauliflora Leaf Extract Promotes Wound Healing Through Anti‐Inflammatory, Antioxidant, and Antibacterial Actions

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT Plinia cauliflora (DC.) Kausel (jabuticaba) is traditionally used by Brazilian indigenous communities for therapeutic purposes, including the treatment of wounds and inflammation. This study investigated the phytochemical composition and biological activities of an ethanolic extract derived from P.
Priscila de Lima Paula   +17 more
wiley   +1 more source

Amazonian Cyanobacteria as a Source of Bioactive Compounds With Antimicrobial and Cytotoxic Properties

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT Cyanobacteria are photosynthetic microorganisms known for producing diverse bioactive compounds. This study explores the bioactivity of extracts and fractions from Amazonian cyanobacteria and their pigment and phenolic compound production. A fraction from Synechococcus sp. CACIAM 05 showed cytotoxicity against hCMEC/D3 and MG‐63 cells.
Samuel Cavalcante do Amaral   +8 more
wiley   +1 more source

Composition, Chemical Variability, and Anti‐inflammatory Activity of the Berry Essential Oil of Juniperus phoenicea L. var. Turbinata From Algeria

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT The chemical composition of 66 oil samples isolated from the berries of individual trees of Juniperus phoenicea var. turbinata, collected in six locations from Algeria, was investigated by gas chromatography with flame ionization detection, gas chromatography‐mass spectrometry, and 13C‐nuclear magnetic resonance.
Chérifa Yassamine Osmani   +6 more
wiley   +1 more source

Recent Advances in Isatin–Thiazole Hybrids: Synthesis, Structural Design, and Biological Application

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT Isatin–thiazole hybrids are considered privileged chemical scaffolds due to their broad spectrum of pharmacological properties, making them attractive candidates for drug development. As a result, isatin–thiazole derivatives have emerged as a prominent class of hybrid heterocycles and have been the focus of extensive research in recent years ...
Isadora M. G. Andrade   +4 more
wiley   +1 more source

In Vivo Biosynthesis and Direct Incorporation of Noncanonical Amino Acids into Proteins

open access: yesChemBioChem, EarlyView.
This review evaluates engineered (semi)autonomous cell systems for the biosynthesis and incorporation of noncanonical amino acids (ncAAs) into proteins. While semi‐autonomous cells convert supplied precursors into ncAAs autonomous cells integrate biosynthetic pathways that produce these building blocks intracellularly.
Jan Hendrik Illies   +2 more
wiley   +1 more source

Exploring the Substrate Flexibility of GrsB Thioesterase Leads to the Structural Reassignment of a Gramicidin S Variant

open access: yesChemBioChem, EarlyView.
Investigation of the substrate specificity of gramicidin S synthetase B‐thioesterase reveals stereochemical flexibility, enabling the production of gramicidin S (GS) analogs with L‐ or D‐Ser(Allyl). Structural reassignment of a GS variant (GS‐SA) obtained from precursor‐directed biosynthesis is achieved using liquid chromatography‐mass spectrometry, 1H
Sho Konno   +8 more
wiley   +1 more source

ThiF‐Like Enzyme Chemistry in Primary and Secondary Metabolism

open access: yesChemBioChem, EarlyView.
ThiF‐like enzymes are a widespread protein family found in disparate biosynthetic pathways. They are unified by their use of an NTP to modify a carboxylate, generating an activated species prone to nucleophilic addition. This common intermediate is then targeted by diverse nucleophiles, including persulfide or amino acid side chains, to yield a variety
Keelie S. Butler   +2 more
wiley   +1 more source

Integrated and closed‐loop biorefinery strategies for efficient waste valorization and biofuel production

open access: yesThe Canadian Journal of Chemical Engineering, EarlyView.
Abstract Advancements in biofuel production technologies are essential for reducing global dependence on fossil fuels and addressing their overexploitation. Many valuable components of biomass, such as cellulose, hemicellulose, and lignin, remain underused in traditional biorefineries, which typically rely on a single feedstock to produce a primary ...
Marcos Paulo Patta Granado   +5 more
wiley   +1 more source

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