Results 261 to 270 of about 275,672 (375)

Evaluating the Therapeutic Potential of Superoxide Dismutase in a Rat Model of Wet Age‐Related Macular Degeneration

open access: yesFASEB BioAdvances, EarlyView.
Oral Superoxide Dismutase Therapy Mitigates Choroidal Neovascularization in a Laser‐Induced Rat Model of Wet Age‐Related Macular Degeneration. Oral Administration of GF103, a Superoxide Dismutase From Bacillus amyloliquefaciens, Reduces Choroidal Neovascularization (CNV) in a Laser‐Induced CNV Rat Model.
Hyun Chul Jeong   +4 more
wiley   +1 more source

Lytic Transglycosylase Deficiency Increases Susceptibility to β‐lactam Antibiotics But Reduces Susceptibility to Vancomycin in Escherichia coli

open access: yesMicrobiology and Immunology, EarlyView.
ABSTRACT In Staphylococcus aureus, a gram‐positive pathogen, vancomycin‐resistant strains become susceptible to β‐lactam antibiotics, referred to as the “seesaw effect.” However, in gram‐negative bacteria, the phenomenon is less clear. Here, we analyzed the gene‐knockout effects of eight lytic transglycosylases (slt, mltA, mltB, mltC, mltD, mltE, mltF,
Takahiko Kimura   +4 more
wiley   +1 more source

The Impact of Toll‐Like Receptor 5 on Liver Function in Age‐Related Metabolic Disorders

open access: yesAging Cell, EarlyView.
Toll‐like receptor 5 (TLR5) deficiency accelerates age‐related metabolic disorders, leading to obesity, fatty liver, and cellular changes such as lipid accumulation in PMHs (hepatocytes) and activation of HSCs (hepatic stellate cells), which drive fibrosis.
Dong‐Hyun Kim   +9 more
wiley   +1 more source

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