Results 241 to 250 of about 157,484 (311)

Fragmentation of Vancoresmycin Reveals a Strong Dependence on Global Molecular Architecture for Antibacterial Activity

open access: yesChemMedChem, Volume 21, Issue 15, 14 August 2026.
Fragmentation of the natural product vancoresmycin reveals an essential role of global architecture for biological potency. Vancoresmycin is a structurally complex tetramic‐acid‐containing natural product with potent activity against Gram‐positive bacteria, yet its structure–activity relationships remain poorly defined.
Max Schönenbroicher   +8 more
wiley   +1 more source

Extending Cofactor‐Tethered Nanomachines to Complex Multienzyme Redox Cascades in Continuous Flow

open access: yesChemSusChem, Volume 19, Issue 15, 14 August 2026.
Engineered enzyme fusions bearing covalently tethered PEG–nicotinamide cofactors enable intramolecular cofactor retention and recycling within self‐sufficient biocatalytic nanomachines. These nanomachines support cofactor‐autonomous operation of complex redox multienzyme cascades under continuous‐flow conditions, as demonstrated in a 10‐step glucose‐to‐
Zinnia Dsouza   +4 more
wiley   +1 more source

Comparative Efficiency of Two Indigenously Isolated Probiotic Strains on Growth Performance and Health Profile of Advance Fry of Labeo rohita

open access: yesAquaculture, Fish and Fisheries, Volume 6, Issue 4, August 2026.
ABSTRACT Due to variations in the mode of action and efficacy, the “one‐size‐fits‐all” model cannot be applied to probiotics. Thus, selecting specific probiotic strains/species for the selected fish species in a particular culture condition/environment is a prerequisite to acquire maximal benefits.
Imrana Amir   +10 more
wiley   +1 more source

Chitosan-Based Cast Films of Different Molecular Weights for Sustained Activity of <i>Bacillus subtilis</i>. [PDF]

open access: yesPolymers (Basel)
Krastev V   +5 more
europepmc   +1 more source

The ageing holobiont: crosstalk between telomere dynamics, oxidative stress and the gut microbiome

open access: yesBiological Reviews, Volume 101, Issue 4, Page 1877-1903, August 2026.
ABSTRACT The gut tissue is at the frontline of early onset of ageing. It exhibits high cell turnover rates and rapid telomere shortening, which can have systemic effects on the developing or senescing organism. We conducted a literature review of studies on the crosstalk between telomere length dynamics, telomerase activity, oxidative stress, and gut ...
Michael L. Pepke   +2 more
wiley   +1 more source

Phytochemical Composition, In Vitro Antioxidant, Antibacterial, and Antibiofilm Activities of Thymus vulgaris Essential Oil From Tiaret, Algeria

open access: yesChemistry &Biodiversity, Volume 23, Issue 8, August 2026.
Thymus vulgaris essential oil (TvEO), largely composed of thymol, showed strong bactericidal activity with Staphylococcus aureus (S. aureus) being most sensitive. TvEO markedly inhibited MRSA biofilm formation and significantly reduced established biofilms. Molecular docking suggests several TvEO components interact with proteins involved in S.
Soumia Dakhouche, Mouna Mnif, Sami Mnif
wiley   +1 more source

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