Results 41 to 50 of about 3,931,849 (341)
Effects of microwave irradiation on the parameters of hydrogel contact lenses [PDF]
, 2001 Ten brands of hydrogel contact lenses were selected from five of the six British Approved Name lens classification groups to test in vitro the effects of repeated heat disinfection by means of microwave irradiation.
Crabbe, A, Thompson, P
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
The clinical back pain courses described by information available in Danish central registries
BMC Health Services Research, 2022 Background Patients with back pain are often in contact with 2–4 hospital departments when receiving a back pain diagnosis and treatment. This complicates the entire clinical course description.
Maria Iachina +4 more
doaj +1 more source
Robot Scheduling for Assistance and Guidance in Hospitals
Applied Sciences, 2021 At present, the global COVID-19 epidemic has not slowed down. To reduce the contact between people during the epidemic and prevent the epidemic from expanding, we have developed a robot to assist medical staff in patient guidance and communication ...
Cheng-Yan Siao +2 more
doaj +1 more source
Challenges and Prospects for Developing CdS/CdTe Substrate Solar Cells on Mo foils [PDF]
, 2014 ITO/ZnO/CdS/CdTe/Mo solar cells have been grown in the substrate configuration by a combination of close-space sublimation and RF sputtering. A peak efficiency of 8.01% was achieved. A two stage CdCl2 annealing process was developed, with the first stage
Forbes, Ian +20 more
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Wheel/Rail Two-Point Contact Geometry With Back-of-Flange Contact
Volume 5: 6th International Conference on Multibody Systems, Nonlinear Dynamics, and Control, Parts A, B, and C, 2007 In this investigation, a numerical procedure that can be used for the three-dimensional analysis of wheel and rail contact geometry is developed using the constraint contact formulation. The locations of contact points are determined for given lateral and yaw displacements of a wheelset when one-point contact is considered for each wheel, while these ...
SUGIYAMA, Hiroyuki, SUDA, Yoshihiro
openaire +2 more sources
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source