Results 131 to 140 of about 21,143 (274)
Recent progress on the development of hydrogel‐based microneedles for transdermal drug delivery
VIEW, EarlyView.This study provides a comprehensive and up‐to‐date analysis of recent progress in HMN technology, covering fundamental transdermal delivery mechanisms and design principles, biomaterials used in HMN fabrication, drug loading and release strategies, and emerging therapeutic applications.
Mohammad Muhtasim Ittisaf +5 more
wiley +1 more source
Melt Damage and Prevention of Gas Nozzle Tip in Close-Coupled Gas Atomization
JGas atomization is one method for producing fine metal powder. In close-coupled gas atomization, a high-speed gas jet is ejected near the molten metal, and the molten metal is further broken down in the shear layer at the outer edge of the jet, producing
Nazuku Kato +4 more
doaj +1 more source
Varying hydraulic strategies within leaves, stems and roots of coexisting desert shrubs
Functional Ecology, EarlyView.Read the free Plain Language Summary for this article on the Journal blog. Abstract Effective and continuous root‐to‐leaf hydraulic transport is crucial for plant survival and growth during drought. However, the capacity to resist hydraulic dysfunction remains understudied in leaves and roots, especially for desert shrubs.
Wenyue Zhao +7 more
wiley +1 more source
BJU International, EarlyView.Objectives To evaluate the association between operative time (OT) and postoperative complications after percutaneous nephrolithotomy (PCNL) in elderly patients, and to identify a clinically meaningful OT threshold for risk stratification. Patients and Methods A retrospective international multicentre study was performed including patients aged ≥70 ...
Łukasz Nowak +41 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Chemotherapy‐induced peripheral neuropathy (CIPN) is a prevalent and treatment‐resistant side effect of platinum‐based chemotherapy, characterised by mechanical allodynia. Cannabigerol (CBG), a non‐psychoactive cannabinoid, has shown antinociceptive potential, but its site and mechanism of action remain unclear.
Quinn W. Wade +7 more
wiley +1 more source
International Journal of Air-Conditioning and RefrigerationThis study investigates the mechanism of discharge backflow in reciprocating refrigeration compressors and its reduction using carbon fiber composite valve reeds.
Zhong Yang +5 more
doaj +1 more source
Veterinary Surgery, EarlyView.Abstract Objective To determine whether reduced intra‐articular (IA) injection volumes provide complete synovial surface coverage while minimizing leakage following canine elbow arthroscopy. Study design Randomized cadaveric study. Animals Forty elbow joints from 20 canine cadavers weighing >15 kg.
Erin Smith +3 more
wiley +1 more source
Translating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights
The Journal of Physiology, EarlyView.Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies. Printed with permission from ®Anita Impagliazzo Medical Illustration. [Correction added on 2 March
Silvia Marchianò +18 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Acidosis depolarises parasympathetic respiratory motoneurones in the dorsal motor nucleus of the vagus (DMV) and increases their firing frequency by reducing TWIK‐2 channel conductance. Acidosis also activates astrocytes, which further enhance neuronal excitability through NMDA receptor‐dependent glutamatergic signalling.
Daniel P. de Souza +4 more
wiley +1 more source