Results 61 to 70 of about 7,188,407 (346)
Molecular Oncology, EarlyView.Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed +8 more
wiley +1 more source
Ultraviolet Background Radiation
Annual Review of Astronomy and Astrophysics, 1973 The results are reported of observations in narrow bands centered on 1115, 1425, and 1446 A of the flux from an empty high-galactic-latitude region and from several stars. The observations had been obtained with the aid of three ultraviolet-sensitive Geiger counters which were carried on an Aerobee-150 rocket launched from the White Sands missile ...
openaire +3 more sources
Structures in the microwave background radiation [PDF]
Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences, 2013 We compare the actual Wilkinson microwave anisotropy probe maps with artificial, purely statistical maps of the same harmonic content to argue that there are, with confidence level 99.7 per cent, ring-type structures in the observed cosmic microwave background.
Pawel Nurowski +2 more
openaire +2 more sources
Physics of the Cosmic Microwave Background Radiation [PDF]
, 2015 The cosmic microwave background (CMB) radiation provides a remarkable window onto the early universe, revealing its composition and structure. In these lectures we review and discuss the physics underlying the main features of the CMB.
D. Wands, O. F. Piattella, L. Casarini
semanticscholar +1 more source
Molecular Oncology, EarlyView.Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
wiley +1 more source
Molecular Oncology, EarlyView.In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran +3 more
wiley +1 more source
The Astrophysical Journal, 2023 Direct photometric measurements of the cosmic optical background (COB) provide an important point of comparison to both other measurement methodologies and models of cosmic structure formation, and permit a cosmic consistency test with the potential to ...
Teresa Symons +4 more
doaj +1 more source
Cells, 2020 Radiation cystitis is a potential complication following the therapeutic irradiation of pelvic cancers. Its clinical management remains unclear, and few preclinical data are available on its underlying pathophysiology.
C. Helissey +5 more
semanticscholar +1 more source
Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies
FEBS Open Bio, EarlyView.Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa +13 more
wiley +1 more source