Results 111 to 120 of about 197,539 (295)

Endogenous “Time Bomb” – Mislocalized Phospholipase A2 as a Critical Mediator of Ultra‐Rapid Mortality in Sepsis and Acute Lung Injury

open access: yesAdvanced Science, EarlyView.
Phospholipase A2 (PLA2), a dormant enzyme, becomes lethal when activated—collapsing lungs in minutes. Our dual therapy (DOPS + varespladib) boosts survival from 0% to >90% in sepsis/ALI. A breakthrough for acute lung injury treatment. ABSTRACT This study reveals that phospholipase A2 (PLA2), normally stable and nontoxic, can be activated specifically ...
Jianyu Wang   +7 more
wiley   +1 more source

Nonlinear robust adaptive control for bidirectional stabilization system of all-electric tank with unknown actuator backlash compensation and disturbance estimation

open access: yesDefence Technology
Since backlash nonlinearity is inevitably existing in actuators for bidirectional stabilization system of all-electric tank, it behaves more drastically in high maneuvering environments.
Shusen Yuan   +3 more
doaj   +1 more source

Impact of inertia, friction, and backlash upon force control in telemanipulation [PDF]

open access: yes
The mechanical behavior of master controllers of telemanipulators has been a concern of both designers and implementors of telerobotic systems. In general, the literature recommends that telemanipulator systems be constructed that minimize inertia ...
Duffie, Neil A.   +3 more
core   +1 more source

Rethinking the Foundational Critiques of Lawyers in Social Movements [PDF]

open access: yes, 2017
This Article argues that the current moment invites reconsideration of these critiques. The rise of new social movements—from marriage equality to Black Lives Matter to the recent mobilization against President Trump’s immigration order—and the response ...
Cummings, Scott L.
core   +1 more source

DNA Replication Errors Drive Genome‐Wide Small Inverted Triplication Dynamics

open access: yesAdvanced Science, EarlyView.
This study provides insight into the dynamic equilibrium mechanism of a novel structural variant, small inverted triplication (SIT), which is generated by misalignment of the 3’ flap generated under DNA replication stress with palindromic sequence. Alternatively, the end sequence may fold back on itself to form an inverted fragment.
Yi Lei   +12 more
wiley   +1 more source

Optimization Design of Part Tolerance of RV Reducer based on Genetic Algorithm

open access: yesJixie chuandong, 2020
The backlash is one of the important technical indicators of the RV reducer, and there are many design parameters that affect the backlash. Based on the mathematical model between the part processing feature tolerance and cost, the minimum part ...
Xie Xiongwei, Xu Honghai, Guan Tong
doaj  

Stress History Establishes a Transient Tolerant State That Shapes Antibiotic Survival Upon Resuscitation

open access: yesAdvanced Science, EarlyView.
High‐throughput single‐cell analysis of resuscitating bacteria reveals a starvation‐history‐dependent transiently tolerant subpopulation that survives β$\beta$‐lactam exposure by temporarily reducing growth. Distinct from classical persisters, these actively growing yet dynamically modulated cells dominate survival across clinically relevant antibiotic
Kieran Abbott   +5 more
wiley   +1 more source

Evaluation of a high-torque backlash-free roller actuator [PDF]

open access: yes
The results are presented of a test program that evaluated the stiffness, accuracy, torque ripple, frictional losses, and torque holding capability of a 16:1 ratio, 430 N-m (320 ft-lb) planetary roller drive for a potential space vehicle actuator ...
Anderson, William   +2 more
core   +4 more sources

Regional wage convergence in Spain : 1850-1930 [PDF]

open access: yes, 2002
Real wages PPP adjusted are used to analyse labour market integration in Spain. In contrast to earlier research analysing migration and nominal wages rates, our research seems to indicate that a well-integrated labour market had emerged in Spain by 1914 ...
Rosés, Joan R., Sánchez-Alonso, Blanca
core   +1 more source

An Open-Source 7-Axis, Robotic Platform to Enable Dexterous Procedures within CT Scanners

open access: yes, 2019
This paper describes the design, manufacture, and performance of a highly dexterous, low-profile, 7 Degree-of-Freedom (DOF) robotic arm for CT-guided percutaneous needle biopsy.
Norbash, Alexander M.   +3 more
core   +1 more source

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