Results 131 to 140 of about 196,018 (269)

Bioabsorbable Endovascular Adhesive Tape (BEAT) for Improving Vascular Regeneration

open access: yesAdvanced Science, EarlyView.
A bioabsorbable endovascular adhesive tape (BEAT) platform based on a hierarchical polyelectrolyte complex is developed to enhance drug delivery in the DCB system. The coating enables rapid transfer to the vessel, provides short‐term mechanical support, and promotes both immediate transfer and long‐term retention of drugs at the lesion site.
Jiarong Wang   +13 more
wiley   +1 more source

Endogenous “Time Bomb” – Mislocalized Phospholipase A2 as a Critical Mediator of Ultra‐Rapid Mortality in Sepsis and Acute Lung Injury

open access: yesAdvanced Science, EarlyView.
Phospholipase A2 (PLA2), a dormant enzyme, becomes lethal when activated—collapsing lungs in minutes. Our dual therapy (DOPS + varespladib) boosts survival from 0% to >90% in sepsis/ALI. A breakthrough for acute lung injury treatment. ABSTRACT This study reveals that phospholipase A2 (PLA2), normally stable and nontoxic, can be activated specifically ...
Jianyu Wang   +7 more
wiley   +1 more source

极端环境下滤波齿轮传动侧隙分析

open access: yesJixie chuandong, 2012
The backlash of the filter gear using for aerospace can be influenced by the extreme environment,and the size of the backlash is one of the most important factors that influence gear transmission accuracy.Based on the thermal equilibrium and heat ...
马玲, 王家序, 陈杰, 韩念龙
doaj  

Compensation of Backlash for High Precision Tracking Control of Inverted Pendulum by Drive-Anti Drive Mechanisms

open access: yesEngineering Proceedings
Many actuating and electro-mechanical devices are driven by DC motors. Gear trains are used to amplify the torque in these motors. They are used in a wide variety of automotives, robotics, and automation applications. However, gears are prone to backlash
Aisha Akbar Awan, Umar S. Khan
doaj   +1 more source

Ejecta‐Modulated Bubble Dynamics Play a Dominant Role in Stone Retropulsion

open access: yesAdvanced Science, EarlyView.
Stone motion during laser ablation is shown to result primarily from asymmetric cavitation bubble collapse, not from ejecta recoil. This challenges long‐standing assumptions and highlights the dominant role of bubble dynamics in laser–material interactions.
Obed S. Isaac   +4 more
wiley   +1 more source

VE‐Cadherin–Actin Regulation Promotes Mechanotransduction and Monolayer Maturation Involving a Tension‐Sensitive Intermediate State

open access: yesAdvanced Science, EarlyView.
This study investigates how endothelial monolayers balance cohesion and plasticity during mechanical stimulation. In HUVECs, shear stress induces a tension‐sensitive intermediate state in which junctional VE‐cadherin and actomyosin relaxation levels coordinate actin/integrin remodeling. This rapid, reversible state strengthens cell junctions, preserves
Jonas Franz   +11 more
wiley   +1 more source

A Strain Decoupling Packaging Strategy for High‐Fidelity Ultrathin Silicon Shape Sensors for Soft Medical Robotics

open access: yesAdvanced Science, EarlyView.
Reliable soft sensors are essential for precise control in soft medical robots such as endoscopes. We developed ultrathin silicon piezoresistive sensors and their oil‐lubricated slidable packaging, which enables high‐fidelity shape sensing of silicon gauges by mechanically isolating the sensing element within a dual‐layer film.
Hao Liu   +7 more
wiley   +1 more source

Targeted Mitochondrial ECSIT Overexpression Attenuates MASH by Increasing OTUD3 Expression

open access: yesAdvanced Science, EarlyView.
Mitochondrial ECSIT expression is reduced during MASH pathogenesis. Overexpression of mitochondrial ECSIT mitigates steatohepatitis and maintains hepatic metabolic homeostasis. Mechanistically, ECSIT enhances intramitochondrial OTUD3 expression to stabilize SIRT3 through deubiquitination, thus preserving mitochondrial function and impeding disease ...
Yuqing Jiang   +11 more
wiley   +1 more source

双摆线无隙钢球传动间隙调节力矩分析

open access: yesJixie chuandong, 1995
By theory of active tooth transmission,the backlash adjustment moment ot insure important property of the double cycloid no backlash steel ball transmission is studied in the paper, and calculation.
安子军, 曲继方
doaj  

Home - About - Disclaimer - Privacy