Results 121 to 130 of about 5,400 (175)

Aspergillus arachnoiditis post intrathecal baclofen pump insertion

, 2013
This report describes an unusual fungal infection of an intrathecal baclofen pump which, to our knowledge, has not been reported previously. We describe a 39-year-old man with severe lower limb spasticity due to secondary progressive multiple sclerosis ...
Butzkueven, H., Hogg, M., Eisen, D.P., Vivek, V., Kavar, B.   +4 more
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Agressie en onrust na overdosis baclofen

, 2016
BACKGROUND: Baclofen is increasingly prescribed for alcohol dependency. Subsequently, the risk of self-intoxication with this medicinal product is increasing.
Veraart, J, Kaasjager, K, Vinkers, C H, de Witte, L D, Dekker, D, Kromkamp, M   +5 more
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Clonidine reverses methylxanthine-induced potentiation of baclofen antinociception.

, 1985
The effect of clonidine on the antinociceptive effect of methylxanthine/baclofen and dopamine antagonist/baclofen combinations was examined to determine if alterations in noradrenaline turnover might mediate the potentiating effect of these agents ...
Jana Sawynok, STEARDO, LUCA
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Low dose baclofen and standard dose acamprosate had comparable changes in brain glutamate, brain Gamma amino butyric acid (GABA) and craving among patients with alcohol dependence syndrome: A 1H-MRS based open label randomized study

Industrial Psychiatry Journal
Background: Understanding of the mechanism of action of Baclofen as anticraving inalcohol dependence syndrome (ADS) is limited. Aim: Our study aimed to examine and compareearly changes in brain glutamate and GABA with Baclofen and Acamprosate among ...
Akhil Kesan, Pranjal Dey, Sourav Khanra, Samiksha Singhai, Monalisa Boro   +4 more
doaj   +1 more source

The case series of baclofen intoxication

, 2019
Baclofen, a gamma-amino butyric acid type B (GABAb) inhibitor, is commonly used in management of spasticity and other medical conditions, such as alcohol dependency.
Widłak, Karolina, Drankowska, Justyna, Tchórz, Michał, Kościuk, Andrzej, Kos, Michał   +4 more
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Baclofen Intoxication Baklofen aşırı dozu CASE REPORT

, 2010
SUMMARY Baclofen, a derivative of γ-aminobutyric acid, is used for symptomatic relief of skeletal muscle spasm and spasticity. Overdose of this drug can cause profound central nervous system depression, including coma, hypotonia, respiratory depression ...

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The treatment of tetanus with intrathecal baclofen

, 2000
The treatment of severe tetanus generally requires prolonged mechanical ventilation. We describe two cases managed with continuous intrathecal infusion of baclofen via a subcutaneous tunnelled spinal catheter and an abdominal injection port. Baclofen, by
O'Callaghan, J, Scott, P, Fraser, J, Boots, RJ, Lipman, J   +4 more
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Baclofen: clinical data

, 2005
This chapter describes the clincial experience related to the use of Baclofen as a pharmacological treatment of alcohol withdrawal ...
Leggio L., Leggio L, Gessa GL, CAPUTO, FABIO, Abenavoli L, Ferrulli A., Abenavoli L., Caputo F, Agabio R, Colombo G, Addolorato G., Addolorato G, De Lorenzo G., AGABIO, ROBERTA, Gessa G.L., DeLorenzi G, Gasbarrini G., Gessa G. L.   +17 more
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D-baclofen: Is it an antagonist at baclofen receptors?

Progress in Neuro-Psychopharmacology and Biological Psychiatry, 1984
Following intrathecal administration into the spinal subarachnoid space, baclofen produced dose related increases in tail flick latency. L-Baclofen was twice as potent as the DL-racemate and 100 times more potent than D-baclofen. When D-baclofen was injected intrathecally 15 min prior to L-baclofen, the subsequent effect of L-baclofen was markedly ...
J, Sawynok, C, Dickson
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Fluorodensitometric determination of baclofen

The Analyst, 1990
A fluorodensitometric method was developed for the determination of baclofen. The method is based on the reaction of baclofen with 4-chloro-7-nitrobenzofurazan and measurement of the fluorescence intensity at 540 nm after chromatographic separation on a silica-gel plate.
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