Results 101 to 110 of about 5,400 (175)

Orthopedic surgery in children with intrathecal baclofen pumps

Journal of Pediatric Rehabilitation Medicine, 2013
AIMS: Children with cerebral palsy often have severe spasticity leading to deformity that requires multiple orthopedic surgeries. Intrathecal baclofen pump implantation effectively decreases severe spasticity. The objective of this study was to determine
Judith L. Gooch, Molly McFadden, Wende Oberg   +2 more
doaj   +1 more source

Unusual Colonic Iron Deposition Following Prophylactic Supplementation in an Infant: A Case Report

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Iron plays a vital role in physiological functions, and its deposition is typically limited to reticuloendothelial tissues in the presence of excess levels. We report a rare case of colonic iron deposition in a 13‐month‐old child without iron overload or toxicity. Despite a normal serum iron profile and administration of only prophylactic iron
Farid Imanzadeh, Mohammad Mahdi Heidari, Seyyed Ramin Madani, Fatemeh Mahjoub, Somayyeh Jameie   +4 more
wiley   +1 more source

Pediatric Wilson Disease in Sudan: A Rare Case, Sudan Conflict and Diagnostic Challenges

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Wilson disease is rarely reported among African children. Wilson disease is due to a mutation in ATP7B on an autosomal recessive pattern, which causes defective copper excretion and copper accumulation in tissues such as liver and brain.
Amjed Abdu Ali Mohammed, Anaheed Alzubair Mohammed HabeebAllah, Sudad salahaldeen Hassan Mohammed, Aprar Kamal Mohammed Ali Almamoon, Mehad Mortada BadrAlden Ahmed, Arafa Mubarak Abotalib Aref, Fatima Bashir Omer Bashir, Tarig Mohamed Nourallah Altegani, Ahmed Alshafei Elmahi Ahmed   +8 more
wiley   +1 more source

Dose-response effect of baclofen in reducing daily alcohol intake in alcohol dependence: secondary analysis of a randomized, double-blind, placebocontrolled trial. Alcohol Alcohol

, 2011
-Aims: To explore the effect of baclofen in a dose of 20 mg three times per day, compared with the already studied dose of 10 mg three times per day, in the treatment of alcohol dependence.
Giorgio Bedogni, Lorenzo Leggio, Fabio Caputo, Raffaele Landolfi, Giovanni Gasbarrini, Giovanni Addolorato, Silvia Cardone, Anna Ferrulli, Baclofen Study Group   +8 more
core  

Tramadol‐Induced Persistent Singultus: A Case Report on Diagnosis, Mechanism, and Management

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Hiccups, or singultus, are involuntary diaphragmatic contractions followed by the sudden closure of the glottis, resulting in a characteristic sound. These episodes are generally transient but can be classified as acute (lasting < 48 h), persistent (lasting > 48 h), or intractable (lasting > 1 month).
Ambika Nand Jha, Varsha Ratan Gaikwad, Abdullah Al Noman, Pranab Dev Sharma   +3 more
wiley   +1 more source

Baclofen, (how) does it work?: The efficacy and working mechanism of high-dose baclofen in the treatment of alcohol dependence [PDF]

, 2018
In this PhD project the efficacy and the working mechanism of high-dose baclofen for the treatment of alcohol use disorder (AUD) were examined. We conducted a randomized controlled trial (RCT) with a high-dose baclofen group (150 mg/day), a low-dose ...
Beraha Menahem, E.M.
core  

Baclofen-induced morbiliform rashes: a case series

, 2011
Baclofen is a gamma amino butyric acid (GABA) derivative that is a specific agonist at GABA-B receptors. Initially used in the treatment of spasticity, it is now being used in the treatment of alcohol dependence.
Narayana Manjunatha, Saddichha, Sahoo, Sahoo Saddichha, Vivek Benegal, Manjunatha, Narayana, Jayaram, Naveen, Naveen Jayaram, Benegal, Vivek   +7 more
core   +1 more source

Electroconvulsive Therapy for Severe Refractory Tardive Dystonia Without Active Depression: A Case Report

Neuropsychopharmacology Reports, Volume 46, Issue 2, June 2026.
Electroconvulsive therapy produced clinically meaningful improvement in severe refractory tardive dystonia without active depression, including recovery of independent ambulation. However, symptom recurrence after discontinuation highlights the potential need for continuation or maintenance strategies.
Tomohiro Asahi, Yasushi Kawamata, Norio Sugawara, Ryo Maehara, Norio Yasui‐Furukori   +4 more
wiley   +1 more source

Resequencing of the auxiliary GABA(B) receptor subunit gene KCTD12 in chronic tinnitus [PDF]

, 2012
Tinnitus is a common and often incapacitating hearing disorder marked by the perception of phantom sounds. Susceptibility factors remain largely unknown but GABA(B) receptor signaling has long been implicated in the response to treatment and, putatively,
V. Pimentel, Geis, S, Cárdenas-Conejo, E., Angelika eBauer, Cárdenas-Conejo, Z E, Langguth, B, Vanessa ePimentel, J. Itzhacki, Sand, P G, Zuge, Elisabeth, Sandra eGeis, Langguth, Berthold, Kleinjung, Tobias, Berthold eLangguth, Kleinjung, T, Philipp G Sand, Bauer, Angelika, S. Geis, A. Bauer, Itzhacki, J, Geis, Sandra, Itzhacki, Jacob, Elizabeth eCárdenas Conejo Zugey, Pimentel, Vanessa, Z. E. Cárdenas-Conejo, P. G. Sand, Pimentel, V, Tobias eKleinjung, B. Langguth, T. Kleinjung, Jacob eItzhacki, Bauer, A, Sand, Philipp G.   +32 more
core   +1 more source

Anesthesia and Postoperative Pain Management in Hip Reconstructions in Children With Neurodevelopmental Conditions: A Proposal for a Peri‐ and Postoperative Pain Management Protocol

Paediatric and Neonatal Pain, Volume 8, Issue 2, June 2026.
ABSTRACT Progressive hip displacement is a common problem in children with neurodevelopmental conditions, often leading to painful dislocation and impaired function. Hip reconstruction may be necessary to maintain containment but these reconstructions are major surgery in this vulnerable population.
Renée A. van Stralen, Susanne D. Verbaas, Jaap Johannes Tolk, Maaike Dirckx, Frank Weber, Thomas G. de Leeuw   +5 more
wiley   +1 more source