Results 91 to 100 of about 5,400 (175)

The role and uptake of drug and alcohol services in patients with alcohol‐associated acute pancreatitis at a large multisite health service

Internal Medicine Journal, EarlyView.
Abstract Background Alcohol consumption remains an independent risk factor for recurrent presentations of alcohol‐associated acute pancreatitis (AAP). Although there are recognised guidelines for alcohol use disorder (AUD), there are no recommendations on targeting alcohol cessation to reduce recurrence of AAP in guidelines for acute pancreatitis ...
Cindy Ho, Hardesh Dhillon, Alexander Mitropoulos, Eliza Flanagan, Timothy Phan, Joshua Haron Abasszade, Jeremy Tse, Bowen Xia, Kyle Williams, Faris Gondal, Sally Jane Bell, David Jacka, Simon Hew   +12 more
wiley   +1 more source

Clobazam to preserve meaningful engagement in prolonged disorder of consciousness with concurrent seizure disorder

PM&R, EarlyView.
Tatiana Bernstein, Zachary Miklja, Tiffany Wood, Joshua Startup   +3 more
wiley   +1 more source

Effectiveness and Tolerability of Topical Amitriptyline 10% Plus Lidocaine 2% Gel in Adults With Post‐Traumatic Trigeminal Neuropathic Pain: A Real‐World Evidence Study

Journal of Oral Rehabilitation, EarlyView.
A compounded amitriptyline 10% plus lidocaine 2% mucoadhesive gel was associated with substantial pain improvement and favourable tolerability in adults with post‐traumatic trigeminal neuropathic pain (PTNP). These findings support targeted mucosal delivery as a promising practical local option and a potential medication‐sparing strategy, particularly ...
Ashley Lebel, Imen Stambouli, Yves Boucher   +2 more
wiley   +1 more source

Baclofen for alcohol withdrawal.

, 2017
Review question: This review attempted to evaluate the efficacy and safety of baclofen as a therapy for alcohol withdrawal syndrome (AWS) in people with alcoholism.
Liu, Jia, Wang, Lunig
core   +1 more source

Intrathecal Baclofen Infusion Pumps in the Treatment of Spasticity: A Retrospective Cohort Study in a Portuguese Centre

Acta Médica Portuguesa, 2019
Introduction: Spasticity is a complex problem in patients with neurological disorders and may distress their quality of life. Intrathecal baclofen infusion pumps reduce spasticity with low doses and minimal side effects but are not free from ...
Pedro Videira Reis, Catarina Rocha Vieira, Ana Cristina Midões, Virginia Rebelo, Paula Barbosa, Armanda Gomes   +5 more
doaj   +1 more source

Safety Challenges of Using High Dose Baclofen for Alcohol Use Disorder: A Focused Review

Frontiers in Psychiatry, 2018
Since the early 2000s, the gamma-aminobutyric acid type B (GABA-B) receptor agonist baclofen has been extensively used for treating alcohol use disorder (AUD).
Benjamin Rolland, Benjamin Rolland, Nicolas Simon, Nicolas Franchitto   +3 more
doaj   +1 more source

Baclofen in the Treatment of Alcohol Use Disorder

, 2019
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject.

core   +2 more sources

Chiral (Stereoselective) Drugs, Asymmetric Synthesis, and Racemic Resolution Methods

Chirality, Volume 38, Issue 7, July 2026.
Chirality is crucial in drug development since both biological targets in the organism and the majority of pharmaceutical compounds are chiral. The synthesis and resolution of chiral compounds are critical steps while developing chiral drugs. Asymmetric synthesis and racemic resolution are the two most common methods for obtaining enantiopure drugs ...
Burcu Karayavuz, Cigdem Karaaslan Kirmizioglu   +1 more
wiley   +1 more source

A randomized, open-label, standard controlled, parallel group study of efficacy and safety of baclofen, and chlordiazepoxide in uncomplicated alcohol withdrawal syndrome

Biomedical Journal, 2016
Background: Alcohol withdrawal syndrome (AWS) is a distressing condition, generally controlled by benzodiazepines (BZD's). Baclofen, a gamma-aminobutyric acid-B (GABAB) agonist, has also shown promising results in controlling AWS.
K. Girish, K. Vikram Reddy, Lakshmi V. Pandit, H.P. Pundarikaksha, R. Vijendra, K. Vasundara, R. Manjunatha, Moulya Nagraj, R. Shruthi   +8 more
doaj   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, Volume 92, Issue 6, Page 1787-1808, June 2026.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source