Results 111 to 120 of about 5,400 (175)
Alcohol, Clinical and Experimental Research, Volume 50, Issue 6, June 2026.This study examined the association between trial length and observed medication effect sizes in pharmacotherapy randomized controlled trials (RCTs) for alcohol use disorder (AUD). Secondary meta‐regression analyses of 139 RCTs found no significant differences in observed effect sizes for abstinence‐ or drinking‐based endpoints between shorter (< 12 ...
Malia A. Belnap +6 more
wiley +1 more source
Alcohol, Clinical and Experimental Research, Volume 50, Issue 6, June 2026.In a randomized, double‐blind study of individuals with alcohol use disorder, high‐dose baclofen (75 mg/day) compared with placebo was associated with differences in resting‐state functional connectivity, with higher connectivity in reward and stress‐related regions and lower connectivity in attentional and salience networks.
Warren B. Logge +5 more
wiley +1 more source
Alimentary Pharmacology &Therapeutics, Volume 63, Issue 12, Page 1673-1684, June 2026.We conducted a nationwide, multicenter cohort study using a target trial emulation framework to compare baclofen and acamprosate in patients with compensated alcohol‐associated cirrhosis. After matching, baclofen initiation was associated with a higher 1‐year risk of major adverse liver outcomes, driven primarily by hepatic encephalopathy, particularly
Yee Hui Yeo +13 more
wiley +1 more source
Baclofen und Baclofen-Prodrugs: Deskriptive und mechanistische Studien zum Membrantransport
, 2012 Baclofen wird zur Behandlung von schweren spastischen Zuständen eingesetzt. Frühere Studien zeigten, dass die Konzentration von Baclofen im Zentralnervensystem (ZNS) nach peroraler oder intravenöser Applikation nur sehr gering sind und es somit schwierig
Pendl, Elisabeth
core
Clarifying Terminology in Chronic Cough: The Evolving Role of Cough Hypersensitivity Syndrome
The Clinical Respiratory Journal, Volume 20, Issue 6, June 2026.This review clarifies the definitions and relationships among ICC, UCC, and RCC, and introduces cough hypersensitivity syndrome (CHS) as an important pathophysiological framework for understanding chronic cough. Within this framework, CHS provides a mechanism‐based perspective that may complement existing terminology, guide future research, and improve
Zihang Wang +8 more
wiley +1 more source
Aseptic meningitis after intrathecal baclofen injection.
, 2006 International audienceStUDY DESIGN: Two case reports of aseptic meningitis after intrathecal baclofen injection. OBJECTIVES: To report an unusual complication of intrathecal baclofen injection during test injections.
Bussel, B. +9 more
core +1 more source
Malfunction of SynchroMed II Baclofen Pump Delivers a Near-Lethal Baclofen Overdose
, 2010 <i>Introduction:</i> Intrathecal baclofen therapy using implantable pumps is an established treatment for spasticity. The pumps occasionally experience serious malfunction.
P. Matsota +4 more
core +2 more sources
Acute psychosis following baclofen overdose
Baclofen is widely used as a muscle relaxant in neurological and other physical health conditions, as well as for its anticraving effects in substance use disorder.
Kelbrick, Marlene +4 more
core +1 more source
Is Oral Baclofen Effective in Neonatal Hypertonia?
, 2011 Cerebral palsy is often associated with spasticity. This study was designed to evaluate the effect of oral baclofen in hypertonic neonates. Retrospective chart review of patients treated with oral baclofen (identified by means of pharmacy records ...
Elizabeth Schulz, Oommen P. Mathew
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