Results 71 to 80 of about 1,065 (181)
Alimentary Pharmacology &Therapeutics, Volume 63, Issue 12, Page 1673-1684, June 2026.We conducted a nationwide, multicenter cohort study using a target trial emulation framework to compare baclofen and acamprosate in patients with compensated alcohol‐associated cirrhosis. After matching, baclofen initiation was associated with a higher 1‐year risk of major adverse liver outcomes, driven primarily by hepatic encephalopathy, particularly
Yee Hui Yeo +13 more
wiley +1 more source
, 2018 OBJECTIVEMany patients undergoing spinal fusion for neuromuscular scoliosis have preexisting neurosurgical implants, including ventricular shunts (VSs) for hydrocephalus and baclofen pumps (BPs) for spastic cerebral palsy. Recent studies have discussed a
Jonathan Dallas +4 more
core +1 more source
Reducing Intrathecal Baclofen Related Infections: Service Evaluation and Best Practice Guidelines [PDF]
, 2020 Objectives: Intrathecal baclofen (ITB) pumps are an effective treatment for spasticity; however infection rates have been reported in 3–26% of patients in the literature.
Shieff, C +16 more
core
Chronic intrathecal baclofen infusion for spasticity: Relationship between pump and host
, 2004 Twenty patients with chronic intractable spinal spasticity were implanted with a totally implantable programmable pump for intrathecal administration of baclofen.
SCAMONI, CARLO +5 more
core +1 more source
Efficacy, Indications, and Safety of Intrathecal Baclofen Pump: A Narrative Review
Purpose of Review: Baclofen, a muscle relaxant that reduces the release of excitatory neurotransmitters in the pre-synaptic neurons stimulating inhibitory neuronal signals in post-synaptic neurons, has been around for over 5 decades.
Siddaiah, Harish +12 more
core +1 more source
Intrathecal baclofen treatment an option in X-linked adrenoleukodystrophy
, 2018 Background: X-linked adrenoleukodystrophy (X-ALD) is a genetic peroxisomal disorder associated with tissue accumulation of very long chain fatty acids (VLCFAs). In approximately one third of affected males, this causes progressive and irreversible damage
Helgi Thor Hjartarson +5 more
core +1 more source
Administración crónica de baclofeno intratecal en espasticidad severa
, 2020 On the basis of previous experimental and clinical studies, 14 patients with severe spasticity due to central or spinal cord damage, resistant to all conservative treatments, were selected after a percutaneous trial period for chronic intrathecal ...
Sánchez-Ledesma, M.J. +4 more
core +1 more source
A Novel Skin and Fascia Opening for Subfascial Inserting of Intrathecal Baclofen Pump
, 2018 OBJECTIVE: The aim of this article is to introduce a new skin and fascia opening for intrathecal baclofen pump implantation in the abdomen, with the purpose of reducing complications related to wound breakdown.METHODS: We introduce a novel way of ...
Fiaschi P. +9 more
core +1 more source
, 2020 Background: Antipsychotic drugs (APDs) are the mainstay of the pharmacological treatment of psychotic disorders like schizophrenia. While the clinical efficacy of APDs has long since been established, the neurobiological mechanisms underlying their ...
Groos, Dominik +6 more
core +1 more source
Intrathecal baclofen associated with improvement of consciousness disorders in spasticity patients
, 2014 Objective Intrathecal baclofen (ITB) pump is a therapeutic option for persistent vegetative state and minimal conscious state patients that have associated spasticity.
Korfias, S.I. +6 more
core