Results 51 to 60 of about 1,065 (181)
Journal of Oral Rehabilitation, EarlyView.A compounded amitriptyline 10% plus lidocaine 2% mucoadhesive gel was associated with substantial pain improvement and favourable tolerability in adults with post‐traumatic trigeminal neuropathic pain (PTNP). These findings support targeted mucosal delivery as a promising practical local option and a potential medication‐sparing strategy, particularly ...
Ashley Lebel +2 more
wiley +1 more source
Intrathecal baclofen withdrawal syndrome- a life-threatening complication of baclofen pump: A case report [PDF]
BMC Clinical Pharmacology, 2004 Abstract Background Intrathecal baclofen pump has been used effectively with increasing frequency in patients with severe spasticity, particularly for those patients who are unresponsive to conservative pharmacotherapy or develop intolerable side effects at therapeutic doses of oral baclofen.
Mohammed, Imran, Hussain, Asif
openaire +2 more sources
Acta Anaesthesiologica Scandinavica, Volume 70, Issue 7, August 2026.ABSTRACT Background Postoperative complications substantially increase morbidity, mortality and healthcare costs. Understanding prognostic factors is essential for risk stratification, targeted prevention strategies, and development of prediction models.
Anders Peder Højer Karlsen +15 more
wiley +1 more source
Imaging Evaluation of Intrathecal Baclofen Pump-Catheter Systems [PDF]
American Journal of Neuroradiology, 2010 ITB pumps are widely used in the treatment of intractable spasticity for many clinical indications, including cerebral palsy and spinal cord injury. High-dose intrathecal administration places the patient at significant risk for withdrawal in the event of device malfunction, necessitating rapid and complete evaluation of the pump-catheter system.
A C, Miracle +5 more
openaire +2 more sources
Arthritis Care &Research, Volume 78, Issue 7, Page 860-874, July 2026.Objective Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies.
Anahita Deboo +88 more
wiley +1 more source
Baclofen Misuse in Clinical Practice: A Case Report on Management Strategies
Clinical Case Reports, Volume 14, Issue 7, July 2026.ABSTRACT Baclofen, a GABA_B receptor agonist, is increasingly linked to misuse and severe withdrawal symptoms, including acute neuropsychiatric manifestations. We present a 26‐year‐old male exhibiting severe substance use disorder and recurrent depressive episodes, accompanied by profound insomnia, suicidal ideation, and visual hallucinations.
Mostafa Yousef +3 more
wiley +1 more source
Intrathecal baclofen pump – a viable therapeutic option in pregnancy [PDF]
Obstetric Medicine, 2010 Baclofen, a gamma-aminobutyric acid analogue, is used as a muscle relaxant and antispasmodic to relieve symptoms in patients with intractable spasticity arising from cerebral or spinal aetiology such as in traumatic brain injury or multiple sclerosis. As it is often used in women of reproductive age, it is imperative to know the safety and associated ...
Saira S, Tandon +2 more
openaire +2 more sources
Intrathecal Baclofen Pump Migration Into the Peritoneal Cavity: A Case Report
, 2016 INTRODUCTION: Intrathecal baclofen pumps are valuable treatment options for those with cerebral palsy. Although subfascial baclofen pump placement is generally preferred over a subcutaneous pump placement due to lower infection rates, rare ...
Lee, Albert +2 more
core +1 more source
Chiral (Stereoselective) Drugs, Asymmetric Synthesis, and Racemic Resolution Methods
Chirality, Volume 38, Issue 7, July 2026.Chirality is crucial in drug development since both biological targets in the organism and the majority of pharmaceutical compounds are chiral. The synthesis and resolution of chiral compounds are critical steps while developing chiral drugs. Asymmetric synthesis and racemic resolution are the two most common methods for obtaining enantiopure drugs ...
Burcu Karayavuz +1 more
wiley +1 more source