Results 31 to 40 of about 109,615 (132)

Polypharmacy among adolescents and adults with cerebral palsy in a clinical setting

open access: yesPM&R, EarlyView.
Abstract Background Adolescents and adults with cerebral palsy often experience multimorbidity related to their condition, which primarily affects movement and posture but is also associated with pain, epilepsy, mood disorders, and other conditions. As such, these patients are often prescribed a range of medications to manage symptoms, thereby putting ...
Caitlin Cassidy   +3 more
wiley   +1 more source

Conditional gene deletion reveals functional redundancy of GABAB receptors in peripheral nociceptors in vivo [PDF]

open access: yes, 2009
Background Gamma-aminobutyric acid (GABA) is an important inhibitory neurotransmitter which mainly mediates its effects on neurons via ionotropic (GABAA) and metabotropic (GABAB) receptors.
Brugger, Stefan   +21 more
core   +1 more source

Risk Factors for Complications Following Paediatric Neuromuscular and Syndromic Scoliosis Correction Surgery: A Systematic Review

open access: yesANZ Journal of Surgery, EarlyView.
ABSTRACT Background Paediatric neuromuscular and syndromic scoliosis patients have multiple medical comorbidities that increase the risk of postoperative complications. There is a lack of consistent literature assessing the specific risk factors for complications following scoliosis correction surgery in this high‐risk cohort.
Mai Pham   +4 more
wiley   +1 more source

Cancer pain: current practice and emerging targets

open access: yesBritish Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye   +5 more
wiley   +1 more source

Safety strategies for everyday community physical activity by adults with cerebral palsy and high support needs: A qualitative case series

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Safety strategies used by adults with complex forms of cerebral palsy when participating in community‐based physical activity were explored in this study. Physical assistance was the main safety strategy in use, provided for four key purposes. The attributes of support people in community settings was key to experiences of safety.
Georgia B McKenzie   +6 more
wiley   +1 more source

Intervention outcomes of children with non‐degenerative dystonia and associated hyperkinetic movement disorders: A scoping review

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Abstract Aim To identify the outcomes reported in published studies of intervention approaches used with non‐degenerative childhood hyperkinetic movement disorders, including dystonia, dyskinesia, hypertonia, athetosis, chorea, cerebral palsy, involuntary movement, and kernicterus, and map them to the International Classification of Functioning ...
Hortensia Gimeno   +10 more
wiley   +1 more source

Dose–Response Effect of Baclofen in Reducing Daily Alcohol Intake in Alcohol Dependence: Secondary Analysis of A Randomized, Double-Blind, Placebo-Controlled Trial

open access: yes, 2011
Aims: To explore the effect of baclofen in a dose of 20 mg three times per day, compared with the already studied dose of 10 mg three times per day, in the treatment of alcohol dependence.
Leggio L   +7 more
core   +1 more source

Mathematical models of gear rattle in Roots blower vacuum pumps [PDF]

open access: yes, 2006
This paper is concerned with the modelling of gear rattle in Roots blower vacuum pumps. Analysis of experimental data reveals that the source of the noise and vibration problem is the backlash nonlinearity due to gear teeth losing and re-establishing ...
Wilson, RE   +6 more
core   +1 more source

The monitoring of cavitation in centrifugal pumps based on the analysis of vibro-acoustic measurements [PDF]

open access: yes
Cavitation in centrifugal pumps causes damages to pump components and produces high levels of vibration and noise, which not only reduces pump performance but also consumes additional energy.
Gu, Fengshou   +2 more
core   +4 more sources

Pharmacological and non‐pharmacological interventions for managing sleep disorders in children with cerebral palsy: A systematic review

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
xxxxxx Aim To systematically review the effectiveness, safety, and economic evidence of pharmacological and non‐pharmacological interventions for sleep disorders in children with cerebral palsy (CP). Method Databases including MEDLINE, Embase, CENTRAL (the Cochrane Library), International Clinical Trials Registry Platform of the World Health ...
Nishant Jaiswal   +11 more
wiley   +1 more source

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