Results 41 to 50 of about 109,615 (132)

Combined dorsal and ventral rhizotomy in non‐ambulatory individuals with mixed spastic bilateral cerebral palsy: A prospective registry analysis

Developmental Medicine &Child Neurology, EarlyView.
This is the largest North American study of combined dorsal/ventral rhizotomy in non‐ambulatory, bilateral, mixed spastic–dyskinetic cerebral palsy (33 patients). Combined rhizotomy was safe, improved dystonia (Barry–Albright Dystonia Scale), spasticity (modified Ashworth scale), quality of life (Caregiver Priorities and Child Health Index of Life with
Adam C. Glaser, Joon Hyeok Choi, Kristin Buxton, Nahyun Kim, Juliana Mariani, Benjamin J. Shore, Weston T. Northam   +6 more
wiley   +1 more source

Efficacy and Immunological Impact of Intrathecal Baclofen Pumps in Managing Spasticity in Multiple Sclerosis in Adult Patients: A Systematic Review

Sclerosis
Background/Objectives: Multiple sclerosis (MS) is a chronic autoimmune disease marked by inflammatory demyelination in the central nervous system, leading to debilitating spasticity. Managing spasticity in MS remains a challenge, and intrathecal baclofen
Billy McBenedict, Wilhelmina Hauwanga, Anna Pogodina, Jeshua Nathaniel Devan, Kang Suen Goh, Ryan Chun Chien Yau, Berley Alphonse, Lorena Adolphsson, Bruno Lima Pessôa   +8 more
doaj   +1 more source

Serum Baclofen Concentrations in Four Dogs With Baclofen Toxicosis Treated With In‐Series Carbon Hemoperfusion and Hemodialysis

Journal of Veterinary Emergency and Critical Care, EarlyView.
ABSTRACT Objective To report serum baclofen concentrations before, during, and after in‐series carbon hemoperfusion (cHP) and hemodialysis (HD) in four dogs with severe baclofen toxicosis. Series Summary This series involves four dogs with serum samples collected before, during, and after in‐series cHP/HD.
Amanda Spillane, Jiwoong Her, Nahvid Etedali, Joanna Finstad, Catherine Langston   +4 more
wiley   +1 more source

Persistent Post‐Traumatic Brain Injury Hiccups Unresponsive to Standard Agents: Resolution Associated With Levetiracetam Therapy

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Post‐traumatic hiccups are an uncommon but distressing complication of traumatic brain injury (TBI), often resistant to conventional pharmacological agents, and the underlying mechanism may involve central neurological disruption of inhibitory pathways rather than gastrointestinal or metabolic aetiologies. We report a male patient in his early
Rostom Karajeh, Ranya Abu Khalaf, Mostafa Ibraheem Abo Alrob, Saif Khaled Abdalhadi Azzam, Youssef Abdelqader Alsaeed   +4 more
wiley   +1 more source

Characteristics of long-duration inhibitory postsynaptic potentials in rat neocortical neurons in vitro [PDF]

, 1987
1. The characteristics of long-duration inhibitory postsynaptic potentials (l-IPSPs) which are evoked in rat frontal neocortical neurons by local electrical stimulation were investigated with intracellular recordings from anin vitro slice preparation.
Howe, James R., Zieglgänsberger, Walter, Sutor, Bernd   +2 more
core   +1 more source

Multifaceted Treatment and Therapies in the Care of Children with Cerebral Palsy – A Literature Review

Journal of Education, Health and Sport
Introduction and Purpose: Cerebral palsy (CP) is a prevalent neurological disorder in children, characterized by movement, muscle tone, and posture impairments.
Anna Wilewska, Bartosz Pomirski, Agata Pomirska, Julia Biernikiewicz, Milena Biernikiewicz, Konstanty Alabrudziński, Agnieszka Borowiec, Kinga Borowiec, Paulina Kwaśniewska, Patryk Graczyk   +9 more
doaj   +1 more source

Clobazam to preserve meaningful engagement in prolonged disorder of consciousness with concurrent seizure disorder

PM&R, EarlyView.
Tatiana Bernstein, Zachary Miklja, Tiffany Wood, Joshua Startup   +3 more
wiley   +1 more source

The Six Pillars of Lifestyle Medicine in MASLD: An Evidence‐Based Guide

Liver International Communications, Volume 7, Issue 3, September 2026.
ABSTRACT Metabolic dysfunction–associated steatotic liver disease (MASLD) is the most common chronic liver disease worldwide and is projected to affect more than 40% of adults by 2050. Although pharmacologic therapies are emerging, lifestyle modification remains the foundation of management.
Jigyasa Sharma, Kathleen Viveiros
wiley   +1 more source

Syndemic Classes of Unhealthy Alcohol Use Reveal Inequities in Alcohol‐Related Consequences and HIV Care Outcomes

Alcohol, Clinical and Experimental Research, Volume 50, Issue 9, September 2026.
Among 4574 adults with HIV in Kaiser Permanente Northern California, latent class analysis identified four syndemic classes combining alcohol use with co‐occurring conditions: Heavy Use/Complex Behavioral Multimorbidity, Moderate Use/High Cardiometabolic Burden, Low Use/High Medical Morbidity, and Moderate Use/Low Morbidity.
Natalia Van Doren, Michael J. Silverberg, Varada Sarovar, Tory Levine, Alexandra Lea, Stacy A. Sterling, Vanessa A. Palzes, Felicia W. Chi, Andrea H. Kline‐Simon, Maha N. Mian, Elena Cyrus, Lunthita M. Duthely, Typhanye Dyer, Angela M. Heads, Michael Horberg, Janice Y. Tsoh, Derek D. Satre   +16 more
wiley   +1 more source

Chronic Baclofen Abuse and Withdrawal Delirium

, 2011
Baclofen is a GABA-B agonist used for muscle spasticity in disorders such as multiple sclerosis. It has growing applications in the treatment of alcohol dependence [1] and its role in the treatment in other addiction disorders has recently been explored [
Nasti, Julian J., Vlasios Brakoulias, Brakoulias, Vlasios (R19651), Julian J. Nasti   +3 more
core   +1 more source