Results 31 to 40 of about 8,987 (195)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Relato de experiência de uma sequência didática com o uso da experimentação: trabalhando bactérias nos anos finais do Ensino Fundamental

Revista de Ensino de Ciências e Matemática, 2023
O presente estudo objetivou investigar se uma sequência didática com experimentação investigativa e foco no ensino do conteúdo de bactérias oferece caminhos para o desenvolvimento da Alfabetização Científica em uma turma do 6° ano do Ensino Fundamental ...
Adrielly Aparecida de Oliveira, Geovana Inácio Gonçalves, Thais Prado Siqueira-Lores, Rodrigo Claudino Diogo   +3 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Piodermite canina: Revisão de literatura e estudo da prevalência de casos no Hospital Veterinário Universitário da UFPI, Bom Jesus – Brasil

Pubvet, 2018
O escopo desta revisão foi abordar os principais aspectos da piodermite canina, enfatizando a importância da mesma na clínica médica de pequenos animais bem como na saúde pública.
Isael de Sousa Sá, Laize Falcão de Almeida, Caike Pinho de Sousa, Raffaella Maria de Oliveira Batista, Dayanne Anunciação Silva Dantas Lima, Everton Almeida Pereira, Márcio Eduardo de Melo Benvenutti, Felicianna Clara Fonseca Machado, Marcia Paula Oliveira Farias, Manoel Lopes da Silva Filho, Antônio Augusto Nascimento Machado Junior   +10 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

ASPECTOS QUÍMICOS E MICROBIOLÓGICOS DE VINHOS DO RIO GRANDE DO SUL

Ciência Rural, 1992
Foram estudados aspectos químicos e microbiológicos de cem (100) diferentes vinhos adquiridos no comércio do Rio Grande do Sul. Valores mínimos, máximos e médios de anidrido sulfuroso livre e total, etanol, acidez volátil e total, açúcares e pH são ...
Plinho Francisco Hertz, Carlos Eugênio Daudt   +1 more
doaj   +1 more source