Results 151 to 160 of about 232,754 (343)

Early predictors of cognitive trajectories from birth to adolescence in children born extremely preterm

Developmental Medicine &Child Neurology, EarlyView.
At 2 years, 10 years, and 15 years, the presence of early white matter injury (WMI) moderated associations between lower social risk and cognitive functioning in the social disadvantage index group x WMI interactions for combined abilities. Findings suggest that the benefits of low social risk were present in those without early WMI, but are ...
Stephen R. Hooper, Robert M. Joseph, T. Michael O′Shea, Karl C. K. Kuban, Rachana Singh, Jean A. Frazier, Genevieve Taylor, Xianming Tan, Rebecca C. Fry, Hudson P. Santos Jr, on behalf of the ELGAN Study Investigators   +10 more
wiley   +1 more source

Real‐World Use of Emicizumab in Patients With Acquired Haemophilia A: An Interim Safety Analysis of a Large‐Scale Post‑Marketing Surveillance Study

Haemophilia, EarlyView.
ABSTRACT Introduction Acquired haemophilia A (AHA) is a rare autoimmune disorder where the development of autoantibodies to factor (F)VIII neutralise its function, leading to bleeding. Emicizumab has been approved for treating AHA in Japan. Aim This post‐marketing study was performed to primarily examine the use and safety of emicizumab, and indirectly
Midori Shima, Katsuyuki Fukutake, Yoshiyuki Ogawa, Yuta Kamei, Chiaki Sugita, Akinori Yuri, Ryota Kobayashi, Akiko Ioka, Tadashi Matsushita   +8 more
wiley   +1 more source

Aligning Research With Practice: Nursing Home Providers' Priorities for Long‐Term Care Research

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Collaboration between providers and investigators can maximize the impact of research in post‐acute and long‐term care settings, including skilled nursing facilities (SNFs). Involving SNF providers in research from the inception can help ensure that investigators are answering practical, clinically relevant questions that are ...
Blythe G. Chen, Amy Recker, Rosa R. Baier, Ann Reddy, David R. Gifford, Stephanie M. Kissam   +5 more
wiley   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Groeger Sabine Elisabeth, Zhou Yuxi, Yong Jiawen, Wang Lei, Ruf Sabine, Meyle Joerg   +5 more
wiley   +1 more source

Autoimmunity and Periodontitis

Journal of Periodontal Research, EarlyView.
In a microbe‐driven inflammatory environment, peptidyl‐arginine deiminase (PAD) enzymes from neutrophils and Porphyromonas gingivalis citrullinate both microbial and self‐antigens. B cell presentation of citrullinated or self‐mimicking epitopes activates T cells that assist B cells in antibody isotype switching, affinity maturation, epitope spreading ...
Massimo Costalonga, Vivek Thumbigere‐Math, Mark C. Herzberg   +2 more
wiley   +1 more source

Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases

Journal of Periodontal Research, EarlyView.
This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini, George Hajishengallis, Mike Curtis, Giacomo Baima   +3 more
wiley   +1 more source

Comparison of mortality associated with methicillin-resistant and methicillin-susceptible Staphylococcus aureus bacteremia: a meta-analysis.

Clinical Infectious Diseases, 2003
S. Cosgrove, G. Sakoulas, E. Perencevich, M. Schwaber, A. Karchmer, Y. Carmeli   +5 more
semanticscholar   +1 more source

The Oral‐Gut Axis: Bidirectional Interactions Between Microbiome and Diseases

Journal of Periodontal Research, EarlyView.
This study aims to summarize the mechanisms underlying ectopic colonization of the gut by oral pathobionts and the microbial and host factors that regulate this process. ABSTRACT Increased colonization of typically oral microorganisms is frequently observed in the gut mucosa or lumen of individuals with gastrointestinal disorders, including patients ...
Shinya Ebihara, Nobuhiko Kamada
wiley   +1 more source

Impact of Dental Status on Heart Transplantation Outcomes

Oral Diseases, EarlyView.
ABSTRACT Objective Oral infections and poor dental health may contribute to systemic complications after heart transplantation, yet data on their impact is limited. In the absence of standardized dental guidelines for transplant candidates, this study evaluated preoperative dental status and its association with post‐transplant outcomes.
Katharina Theresa Obermeier, Ina Dewenter, Maximilian Vorstandlechner, Maximilian Geyer, Wenko Smolka, Christine Kamla, Madeleine Orban, Christoph S. Mueller, Anusha Abdullah   +8 more
wiley   +1 more source

Therapy With Doxycycline and Hydroxychloroquine Enables Surgical Excision of Ulcerated Cutaneous Granulomas in a Patient With Ataxia Telangiectasia

Pediatric Dermatology, EarlyView.
ABSTRACT The rubella virus vaccine strain can cause granulomas in patients with inborn errors of immunity that may evolve into chronic, recalcitrant ulcers. This report details treatment of ulcerated rubella granulomas in a patient with ataxia telangiectasia with doxycycline and hydroxychloroquine resulting in partial ulcer healing within 4 weeks ...
Luis Murguía‐Favela, Sofia Maruschak‐Love, Robertson A. Harrop, Marie‐Anne Brundler, Kyle Kurek, Kevin Fonseca, Michele L. Ramien   +6 more
wiley   +1 more source