Journal of Paediatrics and Child Health, EarlyView.ABSTRACT Aim Guidelines for neonates presenting to the emergency department (ED) with fever, including fever at home, recommend a full septic work‐up and prompt administration of parenteral antibiotics. However, compliance is unknown. We sought to determine rates of guideline compliance in this population, reasons for non‐compliance and rates and ...
Patrick J. B. Walker +3 more
wiley +1 more source
Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis
Journal of Periodontal Research, EarlyView.A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Sabine Elisabeth Groeger +5 more
wiley +1 more source
Clinical Characteristics and Mortality Predictors of Group B Streptococcus Bacteremia in Adults: A Multicenter Retrospective Cohort Study in Japan, 2015-2024. [PDF]
Open Forum Infect DisOguni K +9 more
europepmc +1 more source
Autoimmunity and Periodontitis
Journal of Periodontal Research, EarlyView.In a microbe‐driven inflammatory environment, peptidyl‐arginine deiminase (PAD) enzymes from neutrophils and Porphyromonas gingivalis citrullinate both microbial and self‐antigens. B cell presentation of citrullinated or self‐mimicking epitopes activates T cells that assist B cells in antibody isotype switching, affinity maturation, epitope spreading ...
Massimo Costalonga +2 more
wiley +1 more source
Bacillus clausii-associated bacteremia following probiotic use: A report of two cases and a review of the literature. [PDF]
IDCasesSanchez SJB +3 more
europepmc +1 more source
Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases
Journal of Periodontal Research, EarlyView.This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini +3 more
wiley +1 more source
The Oral‐Gut Axis: Bidirectional Interactions Between Microbiome and Diseases
Journal of Periodontal Research, EarlyView.This study aims to summarize the mechanisms underlying ectopic colonization of the gut by oral pathobionts and the microbial and host factors that regulate this process. ABSTRACT Increased colonization of typically oral microorganisms is frequently observed in the gut mucosa or lumen of individuals with gastrointestinal disorders, including patients ...
Shinya Ebihara, Nobuhiko Kamada
wiley +1 more source
The Clinical Significance of <i>Streptococcus mitis</i> Bacteremia. [PDF]
Open Forum Infect DisAcuff JH +5 more
europepmc +1 more source
Osteoporosis and Periodontitis: Two‐Way Epidemiological and Mechanistic Evidence
Journal of Periodontal Research, EarlyView.This review investigates the main mechanistic pathways connecting local periodontitis to systemic osteoporosis. Seven interconnected mechanisms are identified. ABSTRACT Osteoporosis and periodontitis are highly prevalent, chronic inflammatory diseases that constitute a major global health burden.
Jia Chang +3 more
wiley +1 more source
Risk Factors for Metastatic Infectious Complications in Patients with Catheter-Related Bloodstream Infection. [PDF]
Antibiotics (Basel)Lanyan A +5 more
europepmc +1 more source