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Recombinant bacterial endotoxin testing: a proven solution

BioTechniques, 2021
Testing of parenteral pharmaceuticals and medical devices for pyrogens (fever-inducing substances) is critical to patient safety. The original rabbit pyrogen test has largely been replaced by different bacterial endotoxin tests based on Limulus amebocyte
Brendan Tindall, Dogan Demircioglu, Thomas Uhlig   +2 more
doaj   +1 more source

Evolution of strain coverage by the multicomponent meningococcal serogroup B vaccine (4CMenB) in France

Human Vaccines & Immunotherapeutics, 2021
The 4CMenB, a protein-based vaccine, was licensed in Europe in 2013 against invasive meningococcal disease caused by serogroup B and is currently implemented in several countries although according to different national strategies.
Eva Hong, Aude Terrade, Alessandro Muzzi, Rosita De Paola, Giuseppe Boccadifuoco, Rita La Gaetana, Ala-Eddine Deghmane, Mariagrazia Pizza, Laura Serino, Muhamed-Kheir Taha   +9 more
doaj   +1 more source

Bacterial orbital cellulitis – A review

Indian Journal of Ophthalmology, 2023
Infections of orbit and periorbita are frequent, leading to significant morbidity. Orbital cellulitis is more common in children and young adults. At any age, infection from the neighboring ethmoid sinuses is a likely cause and is thought to result from ...
Dayakar Yadalla, Rajagopalan Jayagayathri, Karthikeyan Padmanaban, Rajkumar Ramasamy, Ram Rammohan, Sonam Poonam Nisar, Viji Rangarajan, Vikas Menon   +7 more
doaj   +1 more source

PEI‐PLGA nanoparticles significantly enhanced the immunogenicity of IsdB137‐361 proteins from Staphylococcus aureus

Immunity, Inflammation and Disease, 2023
Introduction Staphylococcus aureus seriously threatens human and animal health. IsdB137‐361 of the iron surface determinant B protein (IsdB) from S.
Beiyan Wang, Yazun Dong, Yuwei Cen, Shujie Chen, Xue Wen, Kaiyue Liu, Shuangshuang Wu, Liquan Yu, Yongzhong Yu, Zhanbo Zhu, Jinzhu Ma, Baifen Song, Yudong Cui   +12 more
doaj   +1 more source

Epidemiologic, clinical, and serum markers may improve discrimination between bacterial and viral etiologies of childhood pneumonia

Frontiers in Medicine, 2023
BackgroundDiscrimination of bacterial and viral etiologies of childhood community-acquired pneumonia (CAP) is often challenging. Unnecessary antibiotic administration exposes patients to undue risks and may engender antimicrobial resistance.
Helmia Farida, Rina Triasih, Dewi Lokida, Yan Mardian, Gustiani Salim, Wahyu Nawang Wulan, Deni P. Butar-butar, Rizki Amalia Sari, Arif Budiman, Chakrawati Hayuningsih, Moh Syarofil Anam, Setya Dipayana, Mujahidah Mujahidah, Amalia Setyati, Abu Tholib Aman, Adhella Menur Naysilla, Nurhayati Lukman, Aly Diana, Muhammad Karyana, Ahnika Kline, Aaron Neal, H. Clifford Lane, Herman Kosasih, Chuen-Yen Lau   +23 more
doaj   +1 more source

Multidrug-resistant organism infections correlate with increased mortality in COVID-19 patients: A retrospective, observational cohort study

Bali Journal of Anesthesiology, 2022
Background: The uncontrolled use of antibiotics is a big problem that will lead to antibiotic resistance. One of the recommendations for Corona Virus Disease 2019 (COVID-19) therapy is antibiotics.
I Wayan Sumardika, Frederick Cokro, I Wayan Suranadi, Komang Januartha Putra Pinatih   +3 more
doaj   +1 more source

Prevalence and molecular characteristics of Staphylococcus aureus, including methicillin resistant strains, isolated from bulk can milk and raw milk products in pastoral communities of South-West Uganda

BMC Infectious Diseases, 2017
Background Staphylococcus aureus strains are now regarded as zoonotic agents. In pastoral settings where human-animal interaction is intimate, multi-drug resistant microorganisms have become an emerging zoonotic issue of public health concern.
Benon B. Asiimwe, Rossella Baldan, Alberto Trovato, Daniela M. Cirillo   +3 more
doaj   +1 more source

A clinicopathological diagnostic and therapeutic approach to cytolytic vaginosis: An extremely rare entity that may mimic vulvovaginal candidiasis

Journal of Cytology, 2021
Objectives: Cytolytic vaginosis is a very rare entity that may be clinically misdiagnosed as vulvovaginal candidiasis. The aim of this study was to determine the incidence of cytolytic vaginosis in patients displaying symptoms similar to vulvovaginal ...
Uguray P Hacisalihoglu, Ferruh Acet
doaj   +1 more source

Effects of sodium chloride and methylthioninium chloride on Persian sturgeon, Acipenser persicus (Borodin, 1897): A histopathological and bacteriological study [PDF]

Caspian Journal of Environmental Sciences, 2021
360 pieces of Persian sturgeon fingerlings (1.94 ± 0.75 g) were exposed to various sublethal doses of disinfecting chemicals commonly used in aquaculture such as sodium chloride and methylthioninium chloride in order to investigate their impacts on ...
Roghayeh Fathollahi, Hossein Khara, Zabiyolla Pajand, Alireza Shenavar   +3 more
doaj   +1 more source

Insights into the regulatory function of the ɛ subunit from bacterial F-type ATP synthases: a comparison of structural, biochemical and biophysical data [PDF]

Open Biology, 2018
ATP synthases catalyse the formation of ATP, the most common chemical energy storage unit found in living cells. These enzymes are driven by an electrochemical ion gradient, which allows the catalytic evolution of ATP by a binding change mechanism.
Alexander Krah, Mariel Zarco-Zavala, Duncan G. G. McMillan   +2 more
doaj   +1 more source