Results 111 to 120 of about 4,639,350 (390)
Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis
The Lancet, 2022 Christopher J L Kevin Shunji Fablina Lucien Gisela Authia Chie Murray Ikuta Sharara Swetschinski Robles Aguilar G +175 more
semanticscholar +1 more source
Bacterial Biofilm and its Role in the Pathogenesis of Disease
Antibiotics, 2020 Recognition of the fact that bacterial biofilm may play a role in the pathogenesis of disease has led to an increased focus on identifying diseases that may be biofilm-related.
Lene K. Vestby +3 more
semanticscholar +1 more source
Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
Molecular Oncology, EarlyView.The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova +18 more
wiley +1 more source
Beyond Risk: Bacterial Biofilms and Their Regulating Approaches
Frontiers in Microbiology, 2020 Bacterial biofilms are complex surface attached communities of bacteria held together by self-produced polymer matrixs mainly composed of polysaccharides, secreted proteins, and extracellular DNAs. Bacterial biofilm formation is a complex process and can
Musa Hassan Muhammad +8 more
semanticscholar +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
The Incidence of Co-occurrence of Chlamydial Cervicitis with Bacterial Vaginosis
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2011 Background and Objectives: Bacterial vaginosis is caused by an imbalance in normal vaginal bacterial flora mainly caused by the introduction of pathogenic bacteria.
L Ganji +5 more
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Cerebrospinal fluid levels of extracellular heat shock protein 72: A potential biomarker for bacterial meningitis in children [PDF]
, 2014 Extracellular heat shock protein 72 (Hsp72) is an endogenous danger signal and potential biomarker for critical illness in children. We hypothesized that elevated levels of extracellular Hsp72 in the cerebrospinal fluid (CSF) of children with suspected ...
Kernie, Steven G. +5 more
core +1 more source
Annual Review of BiophysicsBacterial ion fluxes are involved in the generation of energy, transport, and motility. As such, bacterial electrophysiology is fundamentally important for the bacterial life cycle, but it is often neglected and consequently, by and large, not understood.
Lo, Wei-Chang +2 more
openaire +3 more sources
Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management
Molecular Oncology, EarlyView.DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez +5 more
wiley +1 more source
Review of antimicrobial use and considerations in the elderly population
Clinical Interventions in Aging, 2018 Angela Giarratano,1 Samantha EL Green,1 David P Nicolau2 1Department of Pharmacy, Hartford Hospital, Hartford, CT, USA; 2Center for Anti-Infective Research and Development, Hartford Hospital, Hartford, CT, USA Abstract: Pharmacologic management of ...
Giarratano A, Green SEL, Nicolau DP
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