Results 111 to 120 of about 3,652,159 (295)

Bacterial Forensics: Revolutionizing Biochemical Analysis [PDF]

open access: yes, 2016
Eva Childrey is a junior forensic science and chemistry double major working in Dr. Eh- rhardt’s research laboratory at VCU. The main goal of the research conducted in this laboratory is to explore the lipid profiles of different bacterial ...
Cain, Caitlin
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Adaptation kinetics in bacterial chemotaxis [PDF]

open access: yes, 1983
Cells of Escherichia coli, tethered to glass by a single flagellum, were subjected to constant flow of a medium containing the attractant alpha-methyl-DL-aspartate. The concentration of this chemical was varied with a programmable mixing apparatus over a
Berg, Howard C.   +2 more
core   +1 more source

Mechanically-driven spreading of bacterial populations

open access: yes, 2015
The effect of mechanical interactions between cells in the spreading of bacterial populations was investigated in one-dimensional space. A continuum-mechanics approach, comprising cell migration, proliferation, and exclusion processes, was employed to ...
Ngamsaad, Waipot, Suantai, Suthep
core   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

Results of high-risk neutropenia therapy of hematology-oncology patients in a university hospital in Uruguay

open access: yesRevista Brasileira de Hematologia e Hemoterapia, 2015
Background: Febrile neutropenia is an important cause of mortality and morbidity in hematology-oncology patients undergoing chemotherapy. The management of febrile neutropenia is typically algorithm-driven. The aim of this study was to assess the results
Matilde Boada Burutaran   +5 more
doaj   +1 more source

House Flies: Manure, Media, and Microbes [PDF]

open access: yes, 2018
This study was conducted to determine if there is a difference in bacterial abundance in house flies based on sex and rearing environment (manure versus artificial media) for house flies.
Adams, Porter   +3 more
core  

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Antimicrobial Drug Prescribing for Pneumonia in Ambulatory Care

open access: yesEmerging Infectious Diseases, 2005
To determine patterns and predictors of antimicrobial drug use for outpatients with community-acquired pneumonia, we examined office visit and pharmacy claims data of 4 large third-party payer organizations from 2000 to 2002.
Conan MacDougall   +3 more
doaj   +1 more source

Phylogenetic conservation of soil bacterial responses to simulated global changes. [PDF]

open access: yes, 2020
Soil bacterial communities are altered by anthropogenic drivers such as climate change-related warming and fertilization. However, we lack a predictive understanding of how bacterial communities respond to such global changes.
Bouskill, Nicholas J   +4 more
core  

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