Results 61 to 70 of about 4,853,662 (342)

A functional RNase P protein subunit of bacterial origin in some eukaryotes [PDF]

open access: yes, 2011
RNase P catalyzes 5′-maturation of tRNAs. While bacterial RNase P comprises an RNA catalyst and a protein cofactor, the eukaryotic (nuclear) variant contains an RNA and up to ten proteins, all unrelated to the bacterial protein.
Bernal Bayard, Pilar   +5 more
core   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

Synthesis and Estimation of the Insecticide and Antibacterial Activities for Some New Amide Derivatives

open access: yesIndonesian Journal of Chemistry, 2023
In this work, new compounds of amide derivatives (C1-C3) were synthesized through the conversion reaction of p-chloroaniline to diazonium salt (B1), which reacts with aniline to form a new azo-compound (B3).
Zinah Hussein Ali   +4 more
doaj   +1 more source

Rapid phylogenetic analysis of large samples of recombinant bacterial whole genome sequences using Gubbins

open access: yesNucleic Acids Research, 2014
The emergence of new sequencing technologies has facilitated the use of bacterial whole genome alignments for evolutionary studies and outbreak analyses.
N. Croucher   +7 more
semanticscholar   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Berberine and its nanoformulations and extracts: potential strategies and future perspectives against multi-drug resistant bacterial infections

open access: yesFrontiers in Microbiology
The increasing prevalence of antimicrobial resistance (AMR) has led to the gradual decline in the effectiveness of existing antibiotics, posing a significant threat to global health.
Xue Yang   +8 more
doaj   +1 more source

Rupture of a pacemaker lead during the course of infective endocarditis

open access: yesTürk Kardiyoloji Derneği Arşivi, 2013
A 23-year-old male who had a VDDR pacemaker implanted seven years ago due to sick sinus syndrome and recurrent syncope episodes was admitted with symptoms of dyspnea, fever, and tachycardia, which were present for a few days.
Çağdaş Akgüllü   +3 more
doaj   +1 more source

Diverse reductive dehalogenases are associated with Clostridiales-enriched microcosms dechlorinating 1,2-dichloroethane [PDF]

open access: yes, 2015
The achievement of successful biostimulation of active microbiomes for the cleanup of a polluted site is strictly dependent on the knowledge of the key microorganisms equipped with the relevant catabolic genes responsible for the degradation process.
Balloi, Annalisa   +8 more
core   +5 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Changes in Biomarkers and Hemodynamics According to Antibiotic Susceptibility in a Model of Bacteremia

open access: yesMicrobiology Spectrum, 2022
Proper selection of susceptible antibiotics in drug-resistant bacteria is critical to treat bloodstream infection. Although biomarkers that guide antibiotic therapy have been extensively evaluated, little is known about host biomarkers targeting in vivo ...
Inwon Park   +11 more
doaj   +1 more source

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