Results 71 to 80 of about 43,367 (250)

The Trimeric Autotransporter Adhesin EmaA and Infective Endocarditis

open access: yesPathogens
Infective endocarditis (IE), a disease of the endocardial surface of the heart, is usually of bacterial origin and disproportionally affects individuals with underlying structural heart disease.
Keith P. Mintz   +2 more
doaj   +1 more source

Identification of a collagen type I adhesin of Bacteroides fragilis. [PDF]

open access: yesPLoS ONE, 2014
Bacteroides fragilis is an opportunistic pathogen which can cause life threatening infections in humans and animals. The ability to adhere to components of the extracellular matrix, including collagen, is related to bacterial host colonisation.
Bruna P G V Galvão   +5 more
doaj   +1 more source

The Landscape of Realized Homologous Recombination in Pathogenic Bacteria [PDF]

open access: yes, 2015
Recombination enhances the adaptive potential of organisms by allowing genetic variants to be tested on multiple genomic backgrounds. Its distribution in the genome can provide insight into the evolutionary forces that underlie traits, such as the ...
Didelot, X   +6 more
core   +2 more sources

Engineered Probiotics: The Next‐Generation Therapeutics to Combat Antibiotic‐Resistant Bacterial Infections

open access: yesFood Frontiers, EarlyView.
Engineered probiotics secretes fusion proteins which potentially neutralized the toxins secreted by other microbial communities. ABSTRACT On a global scale, the escalating burden of infectious diseases, predominantly attributed to bacterial pathogens, especially drug‐resistant strains, has progressed into a critical concern for clinical management and ...
Indu Singh   +11 more
wiley   +1 more source

Targeting Microbiome Metabolites: Reshaping Immunotherapy and Clinical Management Strategies for Colorectal Cancer

open access: yesiMetaMed, EarlyView.
The occurrence and progression of colorectal cancer are intricately linked to metabolites produced by the gut microbiota. Metabolites generated by pathogenic microbial communities can promote colorectal cancer development by reshaping the immune microenvironment.
Xinrui Yang   +3 more
wiley   +1 more source

A novel family of bacterial sialic acid binding adhesins? [PDF]

open access: yes, 2020
of Distinction at Nationwide Children's Annual Research RetreatThird place in Biomedical Sciences at the Denman Undergraduate Research ForumPlatelet binding is a critical step in the development of Infective Endocarditis (IE), an infection of the ...
Patel, Surina
core  

Highly conserved type 1 pili promote enterotoxigenic E. coli pathogen-host interactions [PDF]

open access: yes, 2017
Enterotoxigenic Escherichia coli (ETEC), defined by their elaboration of heat-labile (LT) and/or heat-stable (ST) enterotoxins, are a common cause of diarrheal illness in developing countries.
Begum, Yasmin Ara   +7 more
core   +3 more sources

CAT‐BLAST: Engineered bacteria for robust targeting and elimination of cancer‐associated fibroblasts

open access: yesiMeta, EarlyView.
Cancer‐associated fibroblasts (CAFs) construct a protective stromal barrier that promotes tumor growth and resistance to therapy. To dismantle this, we developed CAT‐BLAST, an engineered bacterial platform designed to potently eliminate these cells. We engineered a safe, high‐expression E.
Mengdi Xu   +7 more
wiley   +1 more source

The Fungal Pathogen Candida albicans Promotes Bladder Colonization of Group B Streptococcus

open access: yesFrontiers in Cellular and Infection Microbiology, 2020
Group B Streptococcus (GBS) is a common cause of bacterial urinary tract infections (UTI) in susceptible populations, including pregnant women and the elderly.
Samuel R. Shing   +7 more
doaj   +1 more source

Adhesins in the virulence of opportunistic fungal pathogens of human

open access: yesMycology, 2021
Aspergillosis, candidiasis, and cryptococcosis are the most common cause of mycoses-related disease and death among immune-compromised patients. Adhesins are cell-surface exposed proteins or glycoproteins of pathogens that bind to the extracellular ...
Amrita Kumari   +7 more
doaj   +1 more source

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