The bacterial cell cycle checkpoint protein Obg and its role in programmed cell death [PDF]
Microbial Cell, 2016 The phenomenon of programmed cell death (PCD), in which cells initiate their own demise, is not restricted to multicellular organisms. Unicellular organisms, both eukaryotes and prokaryotes, also possess pathways that mediate PCD.
Liselot Dewachter +3 more
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The bacterial cell cycle, chromosome inheritance and cell growth [PDF]
Nature Reviews Microbiology, 2019 All viable bacterial cells, whether they divide symmetrically or asymmetrically, must coordinate their growth, division, cell volume and shape with the inheritance of the genome. These coordinated processes maintain genome integrity over generations as chromosomes are duplicated and segregated during each cell cycle, and include the organization of DNA
Rodrigo Reyes-Lamothe +2 more
exaly +6 more sources
Use of the Sucrose Gradient Method for Bacterial Cell Cycle Synchronization [PDF]
Journal of Microbiology & Biology Education, 2012 Although many undergraduate and graduate Cell and Molecular Biology courses study the bacterial cell cycle and the mechanisms that regulate prokaryotic cell division, few laboratory projects exist for the enhanced study of cell cycle characteristics in a
Lin Lin +5 more
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Manipulating the Bacterial Cell Cycle and Cell Size by Titrating the Expression of Ribonucleotide Reductase [PDF]
mBio, 2017 Understanding how bacteria coordinate growth with cell cycle events to maintain cell size homeostasis remains a grand challenge in biology. The period of chromosome replication (C period) is a key stage in the bacterial cell cycle. However, the mechanism
Manlu Zhu +6 more
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Structure and kinase activity of bacterial cell cycle regulator CcrZ. [PDF]
PLoS Genetics, 2022 CcrZ is a recently discovered cell cycle regulator that connects DNA replication initiation with cell division in pneumococci and may have a similar function in related bacteria.
Katherine J Wozniak +3 more
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Successive Paradigm Shifts in the Bacterial Cell Cycle and Related Subjects [PDF]
Life, 2019 A paradigm shift in one field can trigger paradigm shifts in other fields. This is illustrated by the paradigm shifts that have occurred in bacterial physiology following the discoveries that bacteria are not unstructured, that the bacterial cell cycle ...
Vic Norris
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Regulation of Bacterial Cell Cycle Progression by Redundant Phosphatases. [PDF]
J Bacteriol, 2020 Two-component signal transduction systems are widely used by bacteria to adequately respond to environmental changes by adjusting cellular parameters, including the cell cycle. In Caulobacter crescentus , PleC acts as a phosphatase that indirectly protects the response regulator CtrA from ...
Coppine J +5 more
europepmc +7 more sources
Bacterial cell cycle control by citrate synthase independent of enzymatic activity [PDF]
eLife, 2020 Proliferating cells must coordinate central metabolism with the cell cycle. How central energy metabolism regulates bacterial cell cycle functions is not well understood.
Matthieu Bergé +6 more
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Switching modes of chromosome dynamics in the bacterial cell cycle. [PDF]
Proc Natl Acad Sci U S A, 2014 Bacterial cells have no nucleus, and the chromosomal DNA occupies much of the intracellular space in a highly compacted protein–DNA structure called the nucleoid. The genomes of most bacterial species consist of one circular chromosome that is several million base pairs in length. Many studies over several decades have sought to address how so much DNA
Funnell BE.
europepmc +4 more sources
Phase resetting reveals network dynamics underlying a bacterial cell cycle. [PDF]
PLoS Computational Biology, 2012 Genomic and proteomic methods yield networks of biological regulatory interactions but do not provide direct insight into how those interactions are organized into functional modules, or how information flows from one module to another.
Yihan Lin +4 more
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