Results 101 to 110 of about 76,042 (156)

DNA transfer in bacterial conjugation

Journal of Molecular Biology, 1966
Chromosome transfer from Hfr to F − cells was analyzed by labeling the DNA of the Hfr cells with [ 3 H]thymine prior to mating, and/or by labeling any DNA made during mating. The F − cells were either starved of adenine or heavily irradiated with ultraviolet light, with the aim of preventing them from synthesizing DNA.
J D, Gross, L G, Caro
openaire   +2 more sources

Bacterial conjugation-based antimicrobial agents

Plasmid, 2008
A clear imperative exists to generate radically different antibacterial technologies that will reduce the usage of conventional chemical antibiotics. Here we trace one route into this new frontier of drug discovery, a concept that we call the bacterial conjugation-based technologies (BCBT).
Marcin, Filutowicz, Richard, Burgess, Richard L, Gamelli, Jack A, Heinemann, Brigitta, Kurenbach, Sheryl A, Rakowski, Ravi, Shankar   +6 more
openaire   +2 more sources

The Cytology of Bacterial Conjugation

EcoSal Plus, 2004
This review focuses on the membrane-associated structures present at cell-cell contact sites during bacterial conjugation. These transfer proteins/structures have roles in the formation and stabilization of mating contacts and ultimately the passage of substrate across the cell envelope between two bacterial cells.
Gilmour, Matthew W., Lawley, Trevor D., Taylor, Diane E.   +2 more
openaire   +3 more sources

DNA PROCESSING REACTIONS IN BACTERIAL CONJUGATION

Annual Review of Biochemistry, 1995
Bacterial conjugation is an important source of genetic plasticity. The initiation complex for conjugative transfer of transmissible plasmids—the relaxosome—is a specific DNA-protein structure that has been isolated from cells and reconstituted from purified components in vitro.
E, Lanka, B M, Wilkins
openaire   +2 more sources

Bacterial conjugation: everybody's doin' it

Canadian Journal of Microbiology, 1992
Recent evidence suggests that bacterial conjugation is ubiquitous in the bacterial world and that DNA transfer between different genera–kingdoms is possible. It has also been demonstrated that many bacterial gene transfer systems resemble each other at the molecular level and that others are a blend of two or more of these systems.
openaire   +2 more sources

Nanoparticle-drug conjugates treating bacterial infections

Journal of Controlled Release, 2019
The ever increasing scenario of bacterial resistance against commonly available antibiotics is becoming a global threat of major concern, which necessitates the development of new strategies to overcome this hurdle. Conjugation of nanoparticles (NPs) with antimicrobial moieties, such as antibiotics, peptides or different biomolecules, has been one of ...
Pavlina Jelinkova, Aninda Mazumdar, Vishma Pratap Sur, Silvia Kociova, Kristyna Dolezelikova, Ana Maria Jimenez Jimenez, Zuzana Koudelkova, Pawan Kumar Mishra, Kristyna Smerkova, Zbynek Heger, Marketa Vaculovicova, Amitava Moulick, Vojtech Adam   +12 more
openaire   +2 more sources

Anti-bacterial siderophore-aminopenicillin conjugates

2023
An artificial tris-catecolate siderophore with a tripodal backbone and its conjugates with ampicillin and amoxicillin were synthesized. Both conjugates exhibited significantly enhanced in vitro antibacterial activities against Gram-negative species compared to the parent drugs, especially against P. aeruginosa.
Ji, Cheng, Miller, Marvin J, Miller, Patricia A.   +2 more
openaire   +1 more source