Results 31 to 40 of about 1,293,424 (291)

Antibody and antibody fragments site-specific conjugation using new Q-tag substrate of bacterial transglutaminase [PDF]

Cell Death Discovery
During the last few years Antibody-Drug Conjugates (ADCs) have become one of the most active and very promising therapeutic weapons. Lessons learned from the traditional chemical conjugations (via lysine or cysteine residues of the antibodies) and the ...
Meddy El Alaoui, Éva Sivadó, Anne-Catherine Jallas, Lamia Mebarki, Michael R. Dyson, Franck Perrez, Sandrine Valsesia‐Wittmann, Saı̈d El Alaoui   +7 more
openalex   +2 more sources

Bacterial conjugation in the ruminant pathogen Mycoplasma agalactiae is influenced by eukaryotic host factors [PDF]

Applied and Environmental Microbiology
Horizontal gene transfer (HGT) plays a pivotal role in the evolution and adaptation of genome-reduced mycoplasmas. The conjugative properties of these organisms are key in this phenomenon but are largely understudied, particularly in vivo. In the present
M'hamed Derriche, Laurent Xavier Nouvel, Maria Gaudino, Eveline Sagné, Elisa Simon, Hortensia Robert, Gwendoline Pot, Gilles Meyer, Christian de la Fe, Yonathan Arfi, Renaud Maillard, Christine Citti, Eric Baranowski   +12 more
doaj   +2 more sources

Transfer of blaTEM gene between Salmonella and Escherichia coli under processing conditions of animal products: influence of a copper(II) complex [PDF]

Frontiers in Microbiology
The high prevalence of infections caused by contaminated food, coupled with growing antimicrobial resistance, especially through horizontal gene transfer, is a challenge for public health worldwide.
Rosanne Aparecida Capanema Ribeiro, Micaela Guidotti-Takeuchi, Carolyne Ferreira Dumont, Ana Beatriz Garcez Buiatte, Bárbara de Araújo Brum, Thais Jansen Martins, Luana Munique Sousa Ramos, Wendell Guerra, Richard Costa Polveiro, Roberta Torres de Melo, Daise Aparecida Rossi   +10 more
doaj   +2 more sources

Exploring Inhibition of Bacterial Conjugation Coupling Protein TrwB: Novel Ligands to Fight Antimicrobial Resistance Spread. [PDF]

ACS Omega
Gómez-Rubio E, Arana L, Vicario-Martín R, Arbé-Carton K, Garbisu C, Martín-Cámara O, Alkorta I, Martín-Santamaría S.   +7 more
europepmc   +3 more sources

Towards an integrated model of bacterial conjugation [PDF]

FEMS Microbiology Reviews, 2014
Elena Cabezón, Jorge Ripoll‐Rozada, Alejandro Peña, Fernando de la Cruz, Ignacio Aréchaga   +4 more
openalex   +2 more sources

Cryo-EM Structure of a Relaxase Reveals the Molecular Basis of DNA Unwinding during Bacterial Conjugation. [PDF]

Cell, 2017
Ilangovan A, Kay CWM, Roier S, El Mkami H, Salvadori E, Zechner EL, Zanetti G, Waksman G.   +7 more
europepmc   +2 more sources

Chromosome Transfer in Bacterial Conjugation

Bacteriological Reviews, 1965
Edward A. Adelberg, J Pittard
openalex   +4 more sources

ggMOB: Elucidation of genomic conjugative features and associated cargo genes across bacterial genera using genus-genus mobilization networks

Frontiers in Genetics, 2022
Horizontal gene transfer mediated by conjugation is considered an important evolutionary mechanism of bacteria. It allows organisms to quickly evolve new phenotypic properties including antimicrobial resistance (AMR) and virulence.
Gowri Nayar, Ignacio Terrizzano, Ed Seabolt, Akshay Agarwal, Christina Boucher, Jaime Ruiz, Ilya B. Slizovskiy, James H. Kaufman, Noelle R. Noyes   +8 more
doaj   +1 more source

Human intestinal cells modulate conjugational transfer of multidrug resistance plasmids between clinical Escherichia coli isolates. [PDF]

PLoS ONE, 2014
Bacterial conjugation in the human gut microbiota is believed to play a major role in the dissemination of antibiotic resistance genes and virulence plasmids.
Ana Manuel Dantas Machado, Morten O A Sommer   +1 more
doaj   +1 more source

Ubiquitin-like conjugation by bacterial cGAS enhances anti-phage defence

Nature, 2023
Cap2 of the cyclic dinucleotide-based anti-phage immune system functions through a ubiquitin-like conjugation mechanism to regulate cGAS activity. cGAS is an evolutionarily conserved enzyme that has a pivotal role in immune defence against infection^ 1 –
J. Jenson, Tuo Li, Fenghe Du, Chee-Kwee Ea, Zhijian J. Chen   +4 more
semanticscholar   +1 more source