Results 41 to 50 of about 76,042 (156)
Bacterial polysaccharide–protein conjugate vaccines [PDF]
Pure and Applied Chemistry, 1999 The age-related and T-cell independent properties of polysaccharides limit their use as vaccines. These limitations are overcome by covalently binding polysaccharides to proteins to form conjugates. Widespread use of Haemophilus influenzae type b (Hib) conjugates has virtually eliminated systemic infection caused by this pathogen, notably meningitis ...
J. B. Robbins +3 more
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Conjugation Inhibitors Effectively Prevent Plasmid Transmission in Natural Environments
mBio, 2021 Plasmid conjugation is a major route for the spread of antibiotic resistance genes. Inhibiting conjugation has been proposed as a feasible strategy to stop or delay the propagation of antibiotic resistance genes.
Carolina Palencia-Gándara +6 more
doaj +1 more source
Conjugation across Bacillus cereus and kin: A review
Frontiers in Microbiology, 2022 Horizontal gene transfer (HGT) is a major driving force in shaping bacterial communities. Key elements responsible for HGT are conjugation-like events and transmissible plasmids.
Pauline Hinnekens +3 more
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Biomolecules, 2019 The transfer of extended spectrum β-lactamase (ESBL)-genes occurs frequently between different bacteria species. The aim of this study was to investigate the impact of nutrition related stress factors on this transfer.
Eva-Maria Saliu +3 more
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Bacterial conjugation: Running rings around DNA [PDF]
Current Biology, 2001 Helicases are active in many aspects of DNA replication, recombination, repair and transcription. An integral membrane bacterial protein assembly involved in the transfer of DNA between cells has been shown to resemble a ring helicase, suggesting that it hydrolyzes ATP to pump DNA through a central channel.
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Variability of plasmid fitness effects contributes to plasmid persistence in bacterial communities
Nature Communications, 2021 The variability of plasmid fitness effects on wild-type bacterial hosts have been largely unknown until this study, which shows that plasmid persistence increases with bacterial diversity and becomes less dependent on conjugation.
Aida Alonso-del Valle +8 more
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Encounter rates and engagement times limit the transmission of conjugative plasmids.
PLoS GeneticsPlasmid conjugation is a major route for the dissemination of antibiotic resistances and adaptive genes among bacterial populations. Obtaining precise conjugation rates is thus key to understanding how antibiotic resistances spread.
Jorge Rodriguez-Grande +5 more
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Frontiers in Molecular Biosciences, 2016 Burkholderia cenocepacia is both a plant pathogen and the cause of serious opportunistic infections, particularly in cystic fibrosis patients. B. cenocepacia K56-2 harbors a native plasmid named Ptw for its involvement in the Plant Tissue Watersoaking ...
Esther eFernandez-Gonzalez +6 more
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Recent developments in bacterial conjugate vaccines [PDF]
Journal of Medical Microbiology, 1998 Study of the epidemiology of childhood infection reveals that the brunt of disease for a number of invasive bacterial infections is borne by children under the age of 4 years. Haemophilus influenzae type b (Hib), Neisseria meningitidis and Streptococcus pneumoniae, the three most important causes of childhood meningitis, illustrate this phenomenon ...
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Small RNA GadY in Escherichia coli enhances conjugation system of IncP-1 by targeting SdiA
Frontiers in Cellular and Infection MicrobiologyPlasmid-mediated conjugation is a common mechanism for most bacteria to transfer antibiotic resistance genes (ARGs). The conjugative transfer of ARGs is emerging as a major threat to human beings.
Shebin Zhang +26 more
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