Results 31 to 40 of about 1,050,726 (302)

Antimicrobial resistance profiles and molecular characterization of extended-spectrum β-lactamase/AmpC-harboring Klebsiella pneumoniae isolated from clinically ill dogs and cats in South Korea

open access: yesBMC Veterinary Research
Background The emergence of ESBL/AmpC-producing K. pneumoniae is a significant concern in humans and veterinary medicine. This study aims to ascertain the antimicrobial resistance profiles and molecular characteristics of ESBL/AmpC-producing K ...
Yu-Jeong Hwang   +10 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Nationwide surveillance and molecular characterization of methicillin-resistant Staphylococcus pseudintermedius isolated from dogs and cats in South Korea

open access: yesScientific Reports
Staphylococcus pseudintermedius is an important opportunistic pathogen of companion animals, mainly associated with skin and mucous membrane colonization among pets. We aimed to characterize the S.
Su-Jeong Kim   +10 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

The role of airway infection in chronic obstructive pulmonary disease [PDF]

open access: yes, 2006
PhDThis. thesis examines the role of respiratory bacterial and viral infection in the natural history of Chronic Obstructive Pulmonary Disease. The rationale for this study is basedu pon previous data demonstratingt hat airway bacterial colonisationi s
Wilkinson, Thomas Michael Alan
core  

Identification and characterization of small RNAs expressed by Leptospira borgpetersenii serovar Hardjo and their conservation in the genus Leptospira

open access: yesBMC Microbiology
Background Leptospirosis is a global zoonotic disease affecting humans, companion animals, and domestic livestock. Clinical presentation of disease is dependent on complex interactions between host species and pathogenic species, serovars, and strains of
Ellie J Putz   +6 more
doaj   +1 more source

Molecular characterization and drug resistance analysis based on whole-genome sequencing of Listeria monocytogenes isolated from food and patients in Liaocheng City from 2019 to 2022

open access: yesZhongguo shipin weisheng zazhi
ObjectiveThe genomic characteristics, toxicity, drug resistance and genetic diversity of Listeria monocytogenes (Lm) isolated from food and patients based on whole genome sequencing (WGS) in Liaocheng City from 2019 to 2022 were investigated.MethodsThe ...
QIAN Lu   +5 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Stability of multispecies bacterial communities: Signaling networks may stabilize microbiomes [PDF]

open access: yes, 2013
Multispecies bacterial communities can be remarkably stable and resilient even though they consist of cells and species that compete for environmental resources.
Vittorio Venturi   +11 more
core   +1 more source

Bacterial effectors mediate kinase reprogramming through mimicry of conserved eukaryotic motifs

open access: yesEMBO Reports
Bacteria have evolved numerous biochemical processes that underpin their biology and pathogenesis. The small, non-enzymatic bacterial (Salmonella) effector SteE mediates kinase reprogramming, whereby the canonical serine/threonine host kinase GSK3 gains ...
Ioanna Panagi   +15 more
doaj   +1 more source

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