Results 101 to 110 of about 783,196 (311)

Coacervates Made of Elastin‐Like Polypeptides Fused with Melanocyte‐Stimulating Hormone and Monocyte Chemoattractant Protein Enhance Skin Wound Healing in Spinal Cord‐Injured Mice

Advanced Healthcare Materials, EarlyView.
Pressure skin wounds are frequent complications after spinal cord injury (SCI), with impaired healing due to vascular and immune deficits. Elastin‐like polypeptides (ELP) fused to α‐MSH (MSH‐ELP) or MCP‐1 (MCP‐ELP) are developed and tested on these wounds. The resulting nanoparticles are non‐toxic and bioactive, and they enhance macrophage recruitment,
Suneel Kumar, Dhruv Patel, Greeshma Manjunath, Shashank Madhavan, Ashley Mathew, Dnyaneshwari Rananavare, Jahnavi Shah, Francois Berthiaume   +7 more
wiley   +1 more source

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source

Synthesis, In silico Molecular Docking Studies and antimicrobial evaluation of Some New Anthracene Derivatives Tagged with Arylidene, Pyridine, Oxazole, and Chromene Moieties as Promising Inhibitors of Bacterial DNA gyrase

, 2022
Hemat M. Dardeer, Ahmed E. Taha, Arafat Toghan, Aboubakr H. Abdelmonsef, M Schiel, G Silbestri, M Alvarez, C Domini, R Gujjarappa, M Albratty, H Alhazmi, A Abu-Hashem, U Fathy, M Gouda, S Mishra, S Patel, C Halpani, T Orlando, P Salbego, F Farias, G Weimer, J Copetti, H Bonacorso, N Zanatta, M Hoerner, J Bern, M Martins, H Rashdan, A Abdel-Aziem, D El-Naggar, S Nabil, M Kasthuri, C Li, K Verma, O Russell, L Dickson, L Mccormick, L Bassit, F Amblard, R Schinazi, M Asif, M Imran, Abida, Y Nayak, S Gaonkar, E Saleh, H Trivedi, V Joshi, B Patel, L Turones, A Martins, L Moreira, S Da, J Fajemiroye, E Costa, A Moustafa, H El-Sayed, S El Rayes, H Morsy, S Abd-Allah, H Ismail, Abd El-Aal, M, Y Wu, Z Guo, W Deng, J Wang, Sd, S Dasari, S Tondepu, L Vadali, N Seelam, T Yakantham, R Sreenivasulu, G Alluraiah, M Tej, R Ramesh Raju, H Saadati-Moshtaghin, B Maleki, R Tayebee, S Kahrobaei, F Abbasinohoji, A Donaire-Arias, A Montagut, R Puig De La Bellacasa, R Estrada-Tejedor, J Teixid, J Borrell, G Singh, ; Diksha, Mohit, P Acharya, D Jethava, M Vasava, Z Bhavsar, M Bhoi, D Rajani, H Patel, S Jindal, K Meena   +99 more
openalex   +1 more source

Bacterial microbiota diversity and composition in red and white wines correlate with plant-derived DNA contributions and botrytis infection [PDF]

, 2020
Alena M. Bubeck, Lena Preiss, Anna Jung, Elisabeth Dörner, Daniel Podlesny, Marija Kulis, Cynthia Maddox, Cesar Arze, Christian Zörb, Nikolaus Merkt, W. Florian Fricke   +10 more
openalex   +1 more source

Dual‐Peptide Nanoplatform: Mesoporous Silica Nanoparticles Functionalized With a Cell‐Penetrating Peptide and Loaded With Rationally Designed Antimicrobial Peptides for Tuberculosis Therapy

Advanced Healthcare Materials, EarlyView.
Machine learning–guided engineering of a plectasin‐derived peptide yields DC05, a potent antimycobacterial candidate. Encapsulation into tuftsin‐functionalized mesoporous silica nanoparticles enhances intracellular delivery, stability, and activity against Mycobacterium tuberculosis while maintaining low cytotoxicity and minimal hemolysis. The combined
Christian S. Carnero Canales, Cesar Augusto Roque‐Borda, Ana Carolina Cerqueira Negri, Oswaldo Ramirez Delgado, Letícia Oliveira Catarin Nunes, Flávia Aparecida Resende, Hernane Barud, Norival Alves Santos‐Filho, Saulo Santesso Garrido, Karen Cristina Oliveira, Alexandra Ivo de Medeiros, Rafael Miguel Sábio, Fernando Rogério Pavan   +12 more
wiley   +1 more source

Merlin, a New Superfamily of DNA Transposons Identified in Diverse Animal Genomes and Related to Bacterial IS1016 Insertion Sequences [PDF]

, 2004
Cédric Feschotte
openalex   +1 more source

Nano‐Engineered Titanium Implants Loaded With Gingival Fibroblasts‐Derived Microvesicles Enhance Early Osseointegration And Soft Tissue Attachment In Vivo

Advanced Healthcare Materials, EarlyView.
Our study showed that human primary gingival fibroblast–derived microvesicles on nano‐engineered titanium implants promote early osseointegration and soft‐tissue attachment in vivo. ABSTRACT Titanium dental implants require both reliable osseointegration and peri‐implant soft tissue seal formation to ensure long‐term success. While osseointegration has
Pingping Han, Chun Liu, Anjana Jayasree, Kamil Sokolowski, Andrew Liaw, Dingbin Liu, Carlos Salomon, Karan Gulati, Ryan SB Lee, Baoxin Huang, Sašo Ivanovski   +10 more
wiley   +1 more source

Ti6Al4V‐Bioglass‐Copper Composites for Load‐Bearing Implants

Advanced Healthcare Materials, EarlyView.
We have designed and manufactured a novel Ti64‐based composite by adding 45S5 bioglass (BG) and copper (Cu). Adding BG on titanium improves wear resistance and biocompatibility, whereas Cu addition improves mechanical strength while providing inherent lifelong bacterial resistance.
Lochan Upadhayay, Bryson White, Susmita Bose, Amit Bandyopadhyay   +3 more
wiley   +1 more source

Conformational Changes Leading to T7 DNA Delivery upon Interaction with the Bacterial Receptor [PDF]

, 2015
Verónica A. González-García, Mar Pulido-Cid, Carmela Garcia‐Doval, Rebeca Bocanegra, Mark J. van Raaij, Jaime Martín‐Benito, Ana Cuervo, José L. Carrascosa   +7 more
openalex   +1 more source

Bacterial DNA in the diagnosis of spontaneous bacterial peritonitis.

Alimentary pharmacology & therapeutics, 2011
Despite inoculation into blood culture bottles, ascitic fluid culture is negative in 50% of cases of spontaneous bacterial peritonitis (SBP).To determine whether 16S rDNA gene detection by real-time polymerase chain reaction (PCR) and sequencing increases the efficacy of culture in microbiological diagnosis of spontaneous bacterial peritonitis.We ...
Soriano, G, Esparcia, O, Montemayor, M, Guarner-Argente, C, Pericas, R, Torras, X, Calvo, N, Roman, E, Navarro, F, Guarner, C, Coll, P   +10 more
openaire   +2 more sources