Results 11 to 20 of about 1,300,345 (298)

Circulating bacterial-derived DNA fragment level is a strong predictor of cardiovascular disease in peritoneal dialysis patients. [PDF]

PLoS ONE, 2015
Circulating bacterial DNA fragment is related to systemic inflammatory state in peritoneal dialysis (PD) patients. We hypothesize that plasma bacterial DNA level predicts cardiovascular events in new PD patients.We measured plasma bacterial DNA level in ...
Cheuk-Chun Szeto, Bonnie Ching-Ha Kwan, Kai-Ming Chow, Jeffrey Sung-Shing Kwok, Ka-Bik Lai, Phyllis Mei-Shan Cheng, Wing-Fai Pang, Jack Kit-Chung Ng, Michael Ho-Ming Chan, Lydia Choi-Wan Lit, Chi-Bon Leung, Philip Kam-Tao Li   +11 more
doaj   +1 more source

Bacterial DNA promotes Tau aggregation [PDF]

Scientific Reports, 2019
AbstractA hallmark feature of Alzheimer’s disease (AD) and other tauopathies is the misfolding, aggregation and cerebral accumulation of tau deposits. Compelling evidence indicates that misfolded tau aggregates are neurotoxic, producing synaptic loss and neuronal damage.
George Tetz, Michelle Pinho, Sandra Pritzkow, Nicolas Mendez, Claudio Soto, Victor Tetz   +5 more
openaire   +2 more sources

The antimicrobial polymer PHMB enters cells and selectively condenses bacterial chromosomes [PDF]

, 2016
To combat infection and antimicrobial resistance, it is helpful to elucidate drug mechanism(s) of action. Here we examined how the widely used antimicrobial polyhexamethylene biguanide (PHMB) kills bacteria selectively over host cells.
A Gentile, B Spellberg, CE Barry, CR Messick, DJ Dwyer, EE Creppy, EF Palermo, FW O’Grady, G Muller, G Muller, G Rusciano, GS Gordon, J Portugal, JD McCool, JM Boberek, JP Armitage, L Good, LP O’Malley, M Mondhe, MA Kohanski, MJ Allen, MJ Allen, MJ Allen, N Nekhotiaeva, Nakashima, P Broxton, P Broxton, P Broxton, P Erbacher, P Gilbert, R de Vries, R Dryselius, R Firdessa, R Spurio, RF Murphy, S Amoils, S Goh, S Wessels, T Ikeda, T Ikeda, T Kornberg, VB Teif   +41 more
core   +3 more sources

The Influence of DNA Extraction and Lipid Removal on Human Milk Bacterial Profiles

Methods and Protocols, 2020
Culture-independent molecular techniques have advanced the characterization of environmental and human samples including the human milk (HM) bacteriome. However, extraction of high-quality genomic DNA that is representative of the bacterial population in
Anna Ojo-Okunola, Shantelle Claassen-Weitz, Kilaza S. Mwaikono, Sugnet Gardner-Lubbe, Heather J. Zar, Mark P. Nicol, Elloise du Toit   +6 more
doaj   +1 more source

Screening for Highly Transduced Genes in Staphylococcus aureus Revealed Both Lateral and Specialized Transduction

Microbiology Spectrum, 2022
Bacteriophage-mediated transduction of bacterial DNA is a major route of horizontal gene transfer in the human pathogen, Staphylococcus aureus. Transduction involves the packaging of bacterial DNA by viruses and enables the transmission of virulence and ...
Janine Zara Bowring, Yue Su, Ahlam Alsaadi, Sine L. Svenningsen, Julian Parkhill, Hanne Ingmer   +5 more
doaj   +1 more source

Narrative Review of Bacterial DNA Extraction: Key Points and Challenges [PDF]

SINAI International Scientific Journal
Extraction of bacterial DNA is a critical step in obtaining high-quality DNA. The overall quality, yield, and integrity of the genomic DNA isolated affects the success of any downstream applications.
Samar Solyman, Manar El Samak
doaj   +1 more source

On the nucleotide distribution in bacterial DNA sequences [PDF]

, 2010
It is probable that the distributional structure of DNA sequences arises from the accumulation of many successive stochastic events such as nucleotide deletions, insertions, substitutions and elongations [1, 2, 3, 4, 5, 6, 7].
Andrew Glenn Hart, Marcelo Sobottka
core   +2 more sources

Adjuvant activity of Pasteurella multocida A strain, Pasteurella multocida B strain and Salmonella typhimurium bacterial DNA on cellular and humoral immunity responses against Pasteurella multocida specific strain infections in Balb/c mice

Asian Pacific Journal of Tropical Medicine, 2018
Objective: To evaluate the effects of Pasteurella multocida (P. multocida) vaccines on the expression and release of antibodies, interleukin (IL)-6 and IL-12 by serum.
Maryam Homayoon, Yahya Tahamtan, Mohammad Kargar, Seyed Mohammad Hossein Hosseini, Abbas Akhavan Sepahy   +4 more
doaj   +1 more source

Presence of multiple bacterial markers in clinical samples might be useful for presumptive diagnosis of infection in cirrhotic patients with culture-negative reports [PDF]

, 2016
Bacterial infections in cirrhotic patients with ascites are associated with a severe prognosis and an increased risk of death. The microbiological standard tests for the diagnosis of suspected infection, based on culture test of blood and ascitic fluid ...
Boaretti, M, Castellani, F, Lleo, M. M., Lucidi, Cristina, Merli, Manuela   +4 more
core   +1 more source

Identification of a Contact-Dependent Growth Inhibition (CDI) System That Reduces Biofilm Formation and Host Cell Adhesion of Acinetobacter baumannii DSM30011 Strain

Frontiers in Microbiology, 2019
Acinetobacter baumannii is a multidrug-resistant nosocomial opportunistic pathogen that is becoming a major health threat worldwide. In this study, we have focused on the A.
Morgane Roussin, Sedera Rabarioelina, Laurence Cluzeau, Julien Cayron, Christian Lesterlin, Suzana P. Salcedo, Sarah Bigot, Sarah Bigot   +7 more
doaj   +1 more source