Results 21 to 30 of about 805,503 (266)
Control of bacterial DNA supercoiling [PDF]
Molecular Microbiology, 1992 SummaryTwo DNA topoisomerases control the level of negative supercoiling in bacterial cells. DNA gyrase introduces supercoils, and DNA topoisomerase I prevents super‐coiling from reaching unacceptably high levels. Perturbations of supercoiling are corrected by the substrate preferences of these topoisomerases with respect to DNA topology and by changes
openaire +2 more sources
High Sensitivity of Shotgun Metagenomic Sequencing in Colon Tissue Biopsy by Host DNA Depletion
Genomics, Proteomics & Bioinformatics, 2023 The high host genetic background of tissue biopsies hinders the application of shotgun metagenomic sequencing in characterizing the tissue microbiota. We proposed an optimized method that removed host DNA from colon biopsies and examined the effect on ...
Wing Yin Cheng +8 more
doaj +1 more source
Canadian Journal of Infectious Diseases and Medical Microbiology, 2005 Three group B Neisseria meningitidis isolates, recovered from meningococcal disease cases in Canada and typed as B:2c:P1.5, were characterized. Multilocus sequence typing showed that all three isolates were related because of an identical sequence ...
Raymond SW Tsang +5 more
doaj +1 more source
Microorganisms, 2023 The gut microbiota has gained increasing attention in recent years due to its significant impact on colorectal cancer (CRC) development and progression.
Robertina Giacconi +14 more
doaj +1 more source
Bacteria-human somatic cell lateral gene transfer is enriched in cancer samples. [PDF]
PLoS Computational Biology, 2013 There are 10× more bacterial cells in our bodies from the microbiome than human cells. Viral DNA is known to integrate in the human genome, but the integration of bacterial DNA has not been described. Using publicly available sequence data from the human
David R Riley +6 more
doaj +1 more source
Electrochemistry Communications, 2021 New emerging bacterial plant diseases are spreading fast in different geographical regions, and effective safety measures have not been found. Xylella fastidiosa (Xf) is a Gram-negative bacterial plant pathogen classified as a priority quarantine pest ...
W.B.S. Machini, A.M. Oliveira-Brett
doaj +1 more source
DNA vaccines for bacterial infections
Immunology & Cell Biology, 1997 DNA vaccines are an exciting development in vaccine technology which may have a special role in preventing viral infections and as ‘theracines’ for cancer. Their use in preventing bacterial infections has, by comparison, been less well documented.
Strugnell, RA +7 more
openaire +4 more sources
Bacterial Extracellular DNA Promotes β-Amyloid Aggregation
Microorganisms, 2021 Alzheimer’s disease is associated with prion-like aggregation of the amyloid β (Aβ) peptide and the subsequent accumulation of misfolded neurotoxic aggregates in the brain.
George Tetz, Victor Tetz
doaj +1 more source
Frontiers in Genetics, 2020 Bacterial infections of root canals and the surrounding dental hard tissue are still a challenge due to biofilm formation as well as the complex root canal anatomy.
Torsten Sterzenbach +4 more
doaj +1 more source
Natural History of DNA-Dependent DNA Polymerases: Multiple Pathways to the Origins of DNA
Viruses, 2023 One of the major evolutionary transitions that led to DNA replacing RNA as the primary informational molecule in biological systems is still the subject of an intense debate in the scientific community.
Sávio Torres de Farias +3 more
doaj +1 more source