Vancomycin-Modified DNA Origami Nanostructures for Targeting Bacterial Pathogens [PDF]
Leineweber, Özge Coşkuner +8 more
openalex +1 more source
A Bifunctional T3SS‐Effector Simultaneously Cleaves Host MAP Kinase and Inhibits PPM1A Phosphatase
Pathogenic bacteria exploit the metalloprotease effector NleD to subvert host defenses. Structural, biochemical, and infection analyses reveal a bifunctional mechanism by which NleD binds and inhibits the host phosphatase PPM1A while preserving its proteolytic activity against MAPKs.
Yaakov Socol +18 more
wiley +1 more source
Comparative pilot study of three commercial kits for bacterial DNA extraction from human subgingival biofilm samples collected with a single paper point. [PDF]
Wäge-Recchioni J +6 more
europepmc +1 more source
Bacterial α‐diversity decreases, but stochasticity and community stability increase across the 15 m‐depth vertical profiles and along the degraded gradient within the active layer. The abundance and interaction of core taxa mainly control community stability in the active and permafrost layers, respectively.
Shengyun Chen +13 more
wiley +1 more source
Circulating Bacterial DNA as a Novel Blood-Based Biomarker in Type 2 Diabetes Mellitus (DM2): Results from the PROMOTERA Study. [PDF]
Giacconi R +19 more
europepmc +1 more source
RNF213 is characterized as a dual‐functional antiviral effector. It directly mediates the degradation of the influenza A virus nucleoprotein (NP) while simultaneously activating the MDA5‐mediated innate immune signaling pathway. This coordinated response establishes a powerful host defense system against viral infection. ABSTRACT Influenza A virus (IAV)
Haoning Li +5 more
wiley +1 more source
Tracking the origin of bacterial DNA in blood: Indication of localized and sporadic transfer from other body sites. [PDF]
Rozenberga M +6 more
europepmc +1 more source
The Role of DNA-binding Specificity in the Evolution of Bacterial Regulatory Networks
Irma Lozada-Chávez +3 more
openalex +2 more sources
RETREG1‐Mediated Reticulophagy is Essential for Dendritic Cell Maturation and Function in Sepsis
Reticulophagy regulator 1 (RETREG1) maintains dendritic cell (DC) maturation and function in early sepsis. Mechanistically, activating transcription factor 6 (ATF6) acts as a direct transcription factor regulating RETREG1 expression in response to sepsis‐induced endoplasmic reticulum (ER) stress.
Ren‐Qi Yao +28 more
wiley +1 more source
Expanding the diversity of bacterial DNA partitioning: A CTP-independent ParAB<i>S</i> system for plasmid partitioning in <i>Streptomyces</i>. [PDF]
Sukhoverkov KV +8 more
europepmc +1 more source

