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Synthetic bacterial vesicles combined with tumour extracellular vesicles as cancer immunotherapy [PDF]

open access: yesJournal of Extracellular Vesicles, 2021
Bacterial outer membrane vesicles (OMV) have gained attention as a promising new cancer vaccine platform for efficiently provoking immune responses. However, OMV induce severe toxicity by activating the innate immune system.
Kyong‐Su Park   +5 more
doaj   +6 more sources

Bacterial extracellular vesicle applications in cancer immunotherapy

open access: yesBioactive Materials, 2023
Cancer therapy is undergoing a paradigm shift toward immunotherapy focusing on various approaches to activate the host immune system. As research to identify appropriate immune cells and activate anti-tumor immunity continues to expand, scientists are ...
Kanika Suri   +4 more
doaj   +5 more sources

Inhibitors of Bacterial Extracellular Vesicles [PDF]

open access: yesFrontiers in Microbiology, 2022
Both Gram-positive and Gram-negative bacteria can secrete extracellular vesicles (EVs), which contain numerous active substances. EVs mediate bacterial interactions with their hosts or other microbes.
Jianwei Chen   +8 more
doaj   +3 more sources

Bacterial extracellular vesicles and their novel therapeutic applications in health and cancer

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
Bacterial cells communicate with host cells and other bacteria through the release of membrane vesicles known as bacterial extracellular vesicles (BEV). BEV are established mediators of intracellular signaling, stress tolerance, horizontal gene transfer,
Niloufar Hosseini-Giv   +6 more
doaj   +3 more sources

Tick extracellular vesicles enable arthropod feeding and promote distinct outcomes of bacterial infection [PDF]

open access: yesNature Communications, 2021
Extracellular vesicles have been implicated in the transmission of pathogens from the arthropod to the human host. Here the authors show that tick-derived extracellular vesicles play a role in feeding and modulate the outcome of bacterial infection.
Adela S. Oliva Chávez   +32 more
doaj   +2 more sources

Bacterial extracellular vesicles: A position paper by the microbial vesicles task force of the Chinese society for extracellular vesicles

open access: yesInterdisciplinary Medicine, 2023
Recently, the interest in extracellular vesicles released by bacteria has rapidly increased. Bacterial extracellular vesicles (BEVs) have been involved in bacteria‐bacteria and bacteria‐host interactions, which strengthen health or bring about various ...
Minghui Wen   +38 more
doaj   +2 more sources

Deciphering psychobiotics’ mechanism of action: bacterial extracellular vesicles in the spotlight

open access: yesFrontiers in Microbiology, 2023
The intake of psychobiotic bacteria appears to be a promising adjunct to neuropsychiatric treatment, and their consumption may even be beneficial for healthy people in terms of mental functioning.
Layla Bleibel   +4 more
doaj   +1 more source

Maternal microbiota communicates with the fetus through microbiota-derived extracellular vesicles

open access: yesMicrobiome, 2023
Background Reports regarding the presence of bacteria in the fetal environment remain limited and controversial. Recently, extracellular vesicles secreted by the human gut microbiota have emerged as a novel mechanism for host-microbiota interaction.
Anna Kaisanlahti   +22 more
doaj   +1 more source

Extracellular Vesicles from Different Pneumococcal Serotypes Are Internalized by Macrophages and Induce Host Immune Responses

open access: yesPathogens, 2021
Bacterial extracellular vesicles are membranous ultrastructures released from the cell surface. They play important roles in the interaction between the host and the bacteria.
Alfonso Olaya-Abril   +5 more
doaj   +1 more source

Bacterial extracellular vesicles control murine norovirus infection through modulation of antiviral immune responses

open access: yesFrontiers in Immunology, 2022
Human norovirus is the primary cause of non-bacterial gastroenteritis globally and is the second leading cause of diarrheal deaths in children in developing countries. However, effective therapeutics which prevent or clear norovirus infection are not yet
Sutonuka Bhar   +7 more
doaj   +1 more source

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