Results 151 to 160 of about 1,488,259 (274)

Nanomedicine‐driven innovations in postoperative cancer immunotherapy: Remodeling tumor microenvironment and precision delivery strategies

BMEMat, EarlyView.
Nanomedicine‐Driven Strategies for Suppressing Postoperative Tumor Recurrence. This schematic illustrates three pivotal nanomedical strategies that synergistically counteract recurrence by targeting residual disease and the immunosuppressive tumor microenvironment within the surgical cavity.
Lisong Pang, Zhuomin Wang, Zhenhua Jin, Ahmed H. Ghonaim, Hengcheng Zhang, Xinyu You, Jinzhuo Ning, Jiaqing Cao, Yang Liu   +8 more
wiley   +1 more source

Bacterial Extracellular Vesicles as Regulators of the Gut Microbiome-Circadian Axis in Inflammatory and Metabolic Diseases. [PDF]

J Microbiol Biotechnol
Choi H, Oh S, Kim Y.
europepmc   +1 more source

From pathogen to “living drug factory” innovative strategies and clinical translation of bacteria as programmable intelligent vectors for cancer therapy

BMEMat, EarlyView.
Engineered bacteria serve as smart, living therapeutics that target tumors, deliver drugs, and remodel immunosuppressive microenvironments. This review highlights their potential to potentiate immunotherapy, radiotherapy, and chemotherapy, offering a promising paradigm for precise and synergistic cancer treatment. Abstract The dynamic interplay between
Haonan Shen, Weichen Zhang, Gaoli Niu, Li Wang, Ruiyan Li, Yueyue Fan, Feixue Lu, Lingling Xu, Xiaoyuan Ji, Yong Kang   +9 more
wiley   +1 more source

Exosome‐mimetic vesicle‐encapsulated multi‐responsive antibacterial hydrogel core‐shell microneedle patch promotes scarless healing of infected wounds

BMEMat, EarlyView.
The core‐shell microneedle patch VP@FNV‐CuO2‐MN was fabricated by encapsulating n‐CuO2 in a moderately crosslinked PVA/CMCS/Borax4 hydrogel shell and VP‐loaded fibroblast membrane nanovesicles (VP@FNV) in a highly crosslinked PVA/CMCS/Borax6 hydrogel core. Upon application to an infected wound, the acidic microenvironment triggers Fenton‐like reactions
Ziwei Jiang, Huihui Zhang, Lianglong Chen, Zhangfeifan Yang, Sai Cao, Yufang He, Xiaoyang Liu, Siew Yee Wong, Xu Li, Hai Zhou, Ziyan Li, Zijun Zheng, Lei Yang   +12 more
wiley   +1 more source

Therapeutic potential of mesenchymal stem cell-derived extracellular vesicles in SARS-CoV-2 and H1N1 influenza-induced acute lung injury

Mesenchymal stem cell (MSC)-derived extracellular vesicles (EVs) have shown anti-inflammatory potential in multiple inflammatory diseases. In the March 2022 issue of the Journal of Extracellular Vesicles, it was shown that EVs from human MSCs can ...
Lötvall, Jan,, Cho, Byong Seung, Lee, Jun Ho, Jeon, Hyungtaek   +3 more
core   +1 more source

Long-Term Stability of Bacterial Extracellular Vesicles Stored at Different Temperatures. [PDF]

J Extracell Biol
Rama Varma A, Borris F, Kant P, Sadtler K, Fathi P.   +4 more
europepmc   +1 more source

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source

The future of Extracellular Vesicles as Theranostics- an ISEV meeting report

The utilization of extracellular vesicles (EVs) in clinical theranostics has rapidly advanced in the past decade. In November 2018, the International Society for Extracellular Vesicles (ISEV) held a workshop on 'EVs in Clinical Theranostic'.
Yang, Fuquan, Huang, Yiyao, Yan, Xiaomei, Liu, Chunchen, Yin, Hang, Song Gho, Yong, Zheng, Lei, Le, Minh T.N., Marcilla Díaz, Antonio, Zou, Xue, Shekari, Faezeh, Falcón-Perez, Juan Manuel, Wang, Haifang, Cheung, Lesley, Xiao, Yu, An, Taixue, Soekmadji, Carolina, Li, Bo, Wang, Qian, O'Driscoll, Lorraine, Shen, Tang Long, Torrecilhas, Ana Claudia, Zhao, Zezhou, Holthofer, Harry B., Pan, Weilun, Chen, Jing   +25 more
core   +1 more source

Bacterial extracellular vesicles in inflammatory diseases: emerging roles and mechanisms. [PDF]

Regen Biomater
Yang C, Bai M, Wan Y, Qian Y, Li Z, Zheng Q, Lv L, Zhang Y, Fan Z, Yang H, Liao Y.   +10 more
europepmc   +1 more source

Beyond antimicrobials: Ecological nano‐strategies for rebalancing dysbiotic oral microbial homeostasis

BMEMat, EarlyView.
Oral microbial homeostasis, a dynamic host‐microbe balance, is vital in infectious diseases. Conventional antibiotics often disrupt this homeostasis, spurring interest in nanomaterials for oral microbial homeostasis rebalancing. This review outlines nanomaterial strategies across three ecological levels (population/community, ecosystem, and cross ...
Chen Hu, Aohan Luan, Yujun Yang, Linlin Wang, Huilin Wang, Ning Wang, Guixin He, Yajie Yang, Rabiya Noor, Jawad Hussain, Longquan Shao   +10 more
wiley   +1 more source