Results 181 to 190 of about 1,488,259 (274)

Oral Bacterial Extracellular Vesicles as Systemic Messengers: A Mouth–Gut–Systemic Axis Paradigm

Gut Medicine, EarlyView.
ABSTRACT Oral microbiome dysbiosis not only associated with localized periodontal disease but also with multiple systemic diseases, including cardiovascular disease, diabetes mellitus, Alzheimer's disease, rheumatoid arthritis, and cancer. However, the efficiency with which intact viable bacteria cross biological barriers to reach distant organs is ...
Yaping Huang, Narisu Hu, Shuang Pan, Sohaib Shujaat, Zhihui Tang, Hongyang Ma   +5 more
wiley   +1 more source

Bacterial Extracellular Vesicles at the Crossroads of Immune Regulation and Biofilm Dynamics: Biogenesis, Comparative Analysis, and Translational Challenges. [PDF]

Biomolecules
Zhang Q, Zhang B, Aazmi MS, Chen L, Yahya MFZR.   +4 more
europepmc   +1 more source

Pharmacological effects of gastrodin: Insight into neurological diseases and mechanism in ferroptosis and pyroptosis

Ibrain, Volume 11, Issue 1, Page 74-83, Spring 2025.
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley   +1 more source

Engineered bacterial extracellular vesicles as next-generation precision postbiotics: strategies, challenges and prospects. [PDF]

Extracell Vesicles Circ Nucl Acids
Chen J, Chen Q, Li B, Pan C, Grau R, Liu T, Li S, Wang Q, Wang Y, Yang Y, Cheng J, Jin Y, Yang G.   +12 more
europepmc   +1 more source

Chronic Prostatitis/Chronic Pelvic Pain Syndrome: Research Progress and Precision Diagnosis‐Therapy Under the Integrated Neuro–Immune–Metabolic–Microbiota Axis Framework

iMetaMed, EarlyView.
Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is increasingly recognized as a systemic disorder rather than a purely local prostate disease. The diagram illustrates the transition from the traditional local prostate‐centered model to a multi‐axis systemic framework involving clinical heterogeneity, local prostatic inflammation, systemic ...
Kun Wang, Jinfei Liu, Qiangsheng Wang, Lei Fan, Ziang Li, Xuexin Yu, Yonghao Chen, Xiaofan Lu, Guiyi Liao, Jialin Meng, Yu Guan   +10 more
wiley   +1 more source

Bacterial extracellular vesicles as multifaceted regulators of human diseases and emerging therapeutic platforms. [PDF]

Theranostics
Wang J, Wang S, Wang Y, Zhang T, Zhang X.   +4 more
europepmc   +1 more source

Butyrate ameliorates acute‐on‐chronic liver failure by regulating macrophage polarization

iMetaOmics, EarlyView.
Multi‐omics profiling identifies progressive microbiota‐metabolism‐immunity axis dysfunction in acute‐on‐chronic liver failure (ACLF), characterized by gut dysbiosis, reduced butyrate production, intestinal barrier disruption, microbial translocation, and pro‐inflammatory macrophage polarization, thereby exacerbating hepatic inflammation and fibrosis ...
Jing Xiao, Hang You, Zongyi Liu, Yong Sun, Yu Zhang, Li Wei, Ning Ling, Hong Ren, Shiying Li, Peng Hu, Mingli Peng   +10 more
wiley   +1 more source

MicroRNA profiling of circulating extracellular vesicles is involved with susceptibility to age-related diseases : relevance to cardiovascular signalling in ageing process

, 2020
Freishtat, R., Siqueira, Ionara Rodrigues, Batabyal, Rachael, Cechinel, Laura Reck   +3 more
core   +1 more source

In situ detection of extracellular vesicles in breast cancer

Extracellular vesicles (EVs) are small vesicles secreted by a variety of cells into the extracellular space. The role of EVs in cancer biology is well established. It's been reported that EVs-mediated intercellular communication can promote cell growth
Pekovic-Vaughan, Vanja, Korać, Bato, Stojanović, Sara, Golić, Igor, Zakić, Tamara, Korać, Aleksandra, Čvoro, Aleksandra, Janković, Aleksandra   +7 more
core  

Lactobacillus derived small RNAs protect against Klebsiella pneumoniae infection

iMeta, EarlyView.
This study reveals that plant‐derived natural products confer protection against carbapenem‐resistant Klebsiella pneumoniae (CRKP) infection via remodeling the gut microbiota, with Lactobacillus identified as the core beneficial genus. Mechanistically, Lactobacillus murinus (L.
Tingting Xu, Xiuying Tao, Dan Fang, Haijie Zhang, Zhiqiang Wang, Yuan Liu   +5 more
wiley   +1 more source