Results 191 to 200 of about 57,489 (234)

Bacterial extracellular vesicles indirectly destabilize a human stem cell-derived blood-brain barrier on-chip through pro-inflammatory stimulation of immune cells.

Lab Chip
Widom LP, Torabian P, Trempel MA, McCloskey MC, Michel LV, McGrath JL, Gaborski TR.   +6 more
europepmc   +1 more source

Engineered endothelial cells targeting and dihydrotanshinone I loaded bacterial extracellular vesicles for atherosclerosis therapy. [PDF]

Bioeng Transl Med
Zhu RR, Zhou XL, Liu YW, Xu R, Deng P, Liu ZY.   +5 more
europepmc   +1 more source

Update on Non‐Biological and RNA‐Based Therapeutics in Chronic Inflammatory Diseases: Precision Medicine Through Small Molecules: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter, I. M. Adcock, C. Benito‐Villalvilla, R. Bianchini, L. Bjermer, G. Caramori, L. Cari, K. F. Chung, Z. Diamant, I. Eguiluz‐Gracia, E. F. Knol, M. Jesenak, F. Levi‐Schaffer, G. Nocentini, L. O'Mahony, O. Palomares, F. Redegeld, M. Sokolowska, B. Van Esch, M. Zurlo, C. Stellato   +20 more
wiley   +1 more source

Isolation of bacterial extracellular vesicles from raw samples using a portable microstructured electrochemical device. [PDF]

Drug Deliv Transl Res
Mantella V, Bienz S, Brigger F, Baulier E, Ramus M, Zoratto N, Honrath S, Naresh K, Sander S, Dengjel J, Zenobi R, Krivitsky V, Leroux JC.   +12 more
europepmc   +1 more source

Iron Physiology and Its Impact on Atopic Diseases: An EAACI Taskforce Report

Allergy, EarlyView.
ABSTRACT Iron is essential for oxygen transport, energy metabolism, and immune regulation. Yet iron deficiency is the most common micronutrient disorder across all age groups, affecting nearly one quarter of the global population. Iron deficiency triggers nutritional immunity, a host defense mechanism that withholds and redistributes iron, contributing
Franziska Roth‐Walter, Ioana Agache, Beatriz Cabanillas, Roberto Berni Canani, Pasquale Comberiati, Holger Garn, Cristina Gomez‐Casado, Karin Hufnagl, Ekaterina Khaleva, Gregorio P. Milani, Daniel Munblit, Nikolaos Douladiris, Liam O'Mahony, Frank Redegeld, Carmen Riggioni, Peter K. Smith, Betty van Esch, Emilia Vassilopoulou, Carina Venter, Diego G. Peroni   +19 more
wiley   +1 more source

Bacterial extracellular vesicles: emerging mediators of gut-liver axis crosstalk in hepatic diseases. [PDF]

Front Cell Infect Microbiol
Zhou Y, Sun Y, Yin P, Zuo S, Li H, Cao K.   +5 more
europepmc   +1 more source

The role of iron in normal and impaired testicular function

Andrology, EarlyView.
Abstract Iron plays a critical role in testicular physiology, impacting spermatogenesis, testosterone production, and overall testicular function. Iron homeostasis is maintained through systemic and cellular regulatory mechanisms, including hepcidin‐mediated systemic iron control and the iron‐responsive element/iron regulatory protein (IRE/IRP) system ...
Aileen Harrer, Esther G. Meyron‐Holtz, Andreas Meinhardt   +2 more
wiley   +1 more source

Genetically-Programmed Hypervesiculation of Lactiplantibacillus Plantarum Increases Production of Bacterial Extracellular Vesicles with Therapeutic Efficacy in a Preclinical Inflammatory Bowel Disease Model. [PDF]

Adv Sci (Weinh)
Pirolli NH, Levy D, Schledwitz A, Moura NS, Sarkar M, Solomon TJ, Powsner EH, Nowak R, Mamczarz Z, Bridgeman CJ, Khan S, Hui A, Anne N, Reus L, Bentley WE, Raufman JP, Jay SM.   +16 more
europepmc   +1 more source

Bacterial extracellular vesicles in osteoarthritis: a new bridge of the gut-joint axis. [PDF]

Gut Microbes
Niu L, Chen W, Yin Z, Tan H, Cui J, Su J.   +5 more
europepmc   +1 more source

Correction to "Synthetic Biology-Based Bacterial Extracellular Vesicles Displaying BMP-2 and CXCR4 to Ameliorate Osteoporosis". [PDF]

J Extracell Vesicles
europepmc   +1 more source