Bacterial extracellular vesicles: An emerging postbiotic
Trends in Food Science and TechnologyJunhua Xie
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Bacterial extracellular vesicles at the interface of gut microbiota and immunity
Bacterial extracellular vesicles (BEVs) are nano-sized lipid-shielded structures released by bacteria and that play an important role in intercellular communication. Their broad taxonomic origins and varying cargo compositions suggest their active participation in significant biological mechanisms. Specifically, they are involved in directly modulating
Nuno Empadinhas +2 more
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The emerging role of bacterial extracellular vesicles in human cancers
AbstractBacterial extracellular vesicles (BEVs) have emerged as pivotal mediators between bacteria and host. In addition to being crucial players in host homeostasis, they have recently been implicated in disease pathologies such as cancer. Hence, the study of BEVs represents an intriguing and rapidly evolving field with substantial translational ...
Yam Jwp
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Engineered bacterial extracellular vesicles for gastrointestinal diseases
Journal of Controlled ReleaseThe gut microbiota, a complex microbial ecosystem within the gastrointestinal (GI) tract, plays a pivotal role in maintaining GI homeostasis. Dysbiosis of this community is increasingly implicated in the pathogenesis of diverse GI disorders. Bacterial extracellular vesicles (bEVs) secreted from gut microbes have emerged as an innovative therapeutic ...
Xinke, Nie +8 more
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Bacterial extracellular vesicles and their associated toxins
2023Bacterial extracellular vesicles (BEV) are spherical nanostructures released by all bacteria and play vital roles in cell communication. In disease-causing bacteria, the release of BEVs can further help with the infection by delivering toxins and virulence factors into host cells.
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Isolation and Proteomic Characterization of Bacterial Extracellular Membrane Vesicles
Current Protein & Peptide Science, 2014The secretion of extracellular membrane vesicles (EMVs) is a common phenomenon that occurs in archaea, bacteria, and mammalian cells. EMVs contain biologically active proteins, which have diverse roles in biological processes. The outer membrane vesicles (OMVs) of Gram-negative bacteria and membrane vesicles (MVs) of Gram-positive bacteria have been ...
Gun-Hwa, Kim +4 more
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Application of bacterial extracellular vesicles in gastrointestinal diseases
Trends in BiotechnologyBacterial extracellular vesicles (BEVs) are nanoscale spherical particles with lipid bilayer membranes containing diverse functional components from their parent bacteria. They exert pivotal effects on bacteria-bacteria and host-bacteria communication.
Yajun Wang +5 more
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Isolation of Bacterial Extracellular Vesicles and Identification of Their Protein Cargo
2023Bacterial membrane vesicles (BMVs) are important effectors in the pathogenesis, virulence, and biofilm formation during different bacterial infections. Because of their structure, BMVs can be applied as drug delivery systems (DDS) or in the production of immunogenic vaccines against different untreated diseases.
Roberto Alvarez-Fernandez, Garcia +4 more
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Bacterial extracellular vesicles: Modulation of biofilm and virulence properties
Acta BiomaterialiaMicrobial pathogens cause persistent infections by forming biofilms and producing numerous virulence factors. Bacterial extracellular vesicles (BEVs) are nanostructures produced by various bacterial species vital for molecular transport. BEVs include various components, including lipids (glycolipids, LPS, and phospholipids), nucleic acids (genomic DNA,
Young-Mog Kim +2 more
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The role of bacterial extracellular vesicles in promoting antibiotic resistance
Critical Reviews in MicrobiologyThe burgeoning proliferation of infections attributed to multidrug-resistant (MDR) bacterial pathogens is profoundly undermining conventional chemotherapeutic modalities, portending a grave menace to global public health. The propagation of drug resistance among bacteria is fundamentally facilitated by bacterial interactions, with extracellular ...
Shaoqi, Qu +6 more
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