Bacterial extracellular vesicles in biofluids as potential diagnostic biomarkers
Expert Review of Molecular Diagnostics, 2022Extracellular vesicles (EVs) are spherical membrane-derived lipid bilayers released by cells. The human microbiota consists of trillions of microorganisms, with bacteria being the largest group secreting microbial EVs. The discovery of bacterial EVs (BEVs) has garnered interest among researchers as potential diagnostic markers, given that the ...
Kar-Yan Su +8 more
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Bacterial extracellular vesicles: An emerging postbiotic
Trends in Food Science and TechnologyJunhua Xie +2 more
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Engineered bacterial extracellular vesicles for gastrointestinal diseases
Journal of Controlled ReleaseThe gut microbiota, a complex microbial ecosystem within the gastrointestinal (GI) tract, plays a pivotal role in maintaining GI homeostasis. Dysbiosis of this community is increasingly implicated in the pathogenesis of diverse GI disorders. Bacterial extracellular vesicles (bEVs) secreted from gut microbes have emerged as an innovative therapeutic ...
Xinke, Nie +8 more
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Isolation and Proteomic Characterization of Bacterial Extracellular Membrane Vesicles
Current Protein & Peptide Science, 2014The secretion of extracellular membrane vesicles (EMVs) is a common phenomenon that occurs in archaea, bacteria, and mammalian cells. EMVs contain biologically active proteins, which have diverse roles in biological processes. The outer membrane vesicles (OMVs) of Gram-negative bacteria and membrane vesicles (MVs) of Gram-positive bacteria have been ...
Gun-Hwa, Kim +4 more
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Application of bacterial extracellular vesicles in gastrointestinal diseases
Trends in BiotechnologyBacterial extracellular vesicles (BEVs) are nanoscale spherical particles with lipid bilayer membranes containing diverse functional components from their parent bacteria. They exert pivotal effects on bacteria-bacteria and host-bacteria communication.
Yajun Wang +5 more
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Isolation of Bacterial Extracellular Vesicles and Identification of Their Protein Cargo
2023Bacterial membrane vesicles (BMVs) are important effectors in the pathogenesis, virulence, and biofilm formation during different bacterial infections. Because of their structure, BMVs can be applied as drug delivery systems (DDS) or in the production of immunogenic vaccines against different untreated diseases.
Roberto Alvarez-Fernandez, Garcia +4 more
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Influences of bacterial extracellular vesicles on macrophage immune functions
Bacterial extracellular vesicles (EVs) are crucial mediators of information transfer between bacteria and host cells. Macrophages, as key effector cells in the innate immune system, have garnered widespread attention for their interactions with bacterial EVs.
Bowei Jiang, Junyun Huang
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The role of bacterial extracellular vesicles in promoting antibiotic resistance
Critical Reviews in MicrobiologyThe burgeoning proliferation of infections attributed to multidrug-resistant (MDR) bacterial pathogens is profoundly undermining conventional chemotherapeutic modalities, portending a grave menace to global public health. The propagation of drug resistance among bacteria is fundamentally facilitated by bacterial interactions, with extracellular ...
Shaoqi, Qu +6 more
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Bacterial extracellular vesicles: Modulation of biofilm and virulence properties
Acta BiomaterialiaMicrobial pathogens cause persistent infections by forming biofilms and producing numerous virulence factors. Bacterial extracellular vesicles (BEVs) are nanostructures produced by various bacterial species vital for molecular transport. BEVs include various components, including lipids (glycolipids, LPS, and phospholipids), nucleic acids (genomic DNA,
Geum-Jae Jeong +2 more
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Environmental and ecological importance of bacterial extracellular vesicles (BEVs)
Science of The Total EnvironmentExtracellular vesicles are unique structures released by the cells of all life forms. Bacterial extracellular vesicles (BEVs) were found in various ecosystems and natural habitats. They are associated with bacterial-bacterial interactions as well as host-bacterial interactions in the environment.
Abeer Ahmed Qaed, Ahmed +1 more
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