Results 51 to 60 of about 1,520,593 (361)

Alternative mechanism for bacteriophage adsorption to the motile bacterium Caulobacter crescentus [PDF]

, 2011
2D and 3D cryo-electron microscopy, together with adsorption kinetics assays of ϕCb13 and ϕCbK phage-infected Caulobacter crescentus, provides insight into the mechanisms of infection.
Ackermann, Adrian, Agabian-Keshishian, B. Ely, Bender, Bendis, Berg, Bradley, Briegel, Brinton, Chibeu, E. R. Wright, Edgar, Evinger, Fukuda, Fukuda, Fukuda, G. J. Jensen, Hinz, Huitema, J. S. Poindexter, Jollick, Kremer, Lagenaur, Lake, Leonard, Leonard, M. Georgieva, P. H. Viollier, Papadopoulos, Poindexter, Poindexter, Pope, Pruggnaller, R. C. Guerrero-Ferreira, Radhakrishnan, Raimondo, Samuel, Schade, SCHMIDT, SCHMIDT, Scholl, Skerker, Sommer, Zheng, Zhilenkov   +45 more
core   +4 more sources

Serological evidence of Francisella tularensis in febrile patients seeking treatment at remote hospitals, northeastern Kenya, 2014–2015

New Microbes and New Infections, 2017
Tularaemia is a highly contagious infectious zoonosis caused by the bacterial agent Francisella tularensis. The aim of this study was to investigate the presence of antibodies to F. tularensis in febrile patients in northeastern Kenya.
J. Njeru, H. Tomaso, K. Mertens, K. Henning, G. Wareth, R. Heller, S. Kariuki, E.M. Fèvre, H. Neubauer, M.W. Pletz   +9 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Etiology of Severe Non-malaria Febrile Illness in Northern Tanzania: A Prospective Cohort Study. [PDF]

, 2013
The syndrome of fever is a commonly presenting complaint among persons seeking healthcare in low-resource areas, yet the public health community has not approached fever in a comprehensive manner.
AJ Bouley, Anne B. Morrissey, B Nadjm, B Nadjm, B Pastorino, BM Greenwood, CA Petti, Charles Muiruri, CIR Chandler, CJ Murray, CJ Murray, DC Clifton, DR Feikin, EA Reddy, Eng Eong Ooi, Grace D. Kinabo, H Reyburn, HM Biggs, JA Berkley, JA Crump, JA Crump, JA Crump, JA Crump, John A. Bartlett, John A. Crump, JT Hertz, K Baltzell, LE Scott, LK Archibald, M Amexo, M Prabhu, Mathieu Picardeau, MD Bajani, MK Mayhood, MM Levine, N Scaramozzino, OS Levine, PA Connolly, PL Petit, R Lozano, Renee L. Galloway, Robert F. Massung, Robyn A. Stoddard, SI Hay, SJ Olsen, SL Brown, SM Graham, SM Lofgren, TJ O'Dempsey, Venance P. Maro, Wilbrod Saganda, William L. Nicholson, YL Lai   +52 more
core   +6 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Downregulation of Mcl-1 has anti-inflammatory pro-resolution effects and enhances bacterial clearance from the lung [PDF]

, 2013
Phagocytes not only coordinate acute inflammation and host defense at mucosal sites, but also contribute to tissue damage. Respiratory infection causes a globally significant disease burden and frequently progresses to acute respiratory distress syndrome,
A Cross, A G Rossi, A Planaguma, AE Leitch, AE Leitch, AG Rossi, AL Alessandri, B Dibbert, BM Fournier, C Akgul, C D Lucas, C Haslett, C Nathan, C T Robb, CD Lucas, CN Serhan, D A Dorward, DA Dorward, DA Moulding, DA Moulding, DA Steimer, DJ Wardle, E Abraham, EE McGrath, GL Bannenberg, GS Worthen, H Liu, HG Folkesson, HM Marriott, I Dzhagalov St, I Nicoletti, J A Marwick, J Liang, JS Savill, K C Allen, K Ganeshan, KP Steinberg, L Fialkow, L Santo, M A Tait, MA Matthay, N Chiang, N Fotouhi-Ardakani, N Hirani, O Eickmeier, R Boxio, R Duffin, S Brode, S Fox, S Fox, S Michlewska, SJ Leuenroth, SL Poe, SP Garrison, T Hideshima, T Tanaka, TR Ulich, U Koedel, Y Liu   +58 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Shigella type-III secretion system effectors counteract the induction of host inflammation and cell death

The EMBO Journal
Many enteric bacterial pathogens deliver virulence effectors to counteract host innate immune responses, such as inflammation and cell death, and colonize the intestinal epithelium.
Hiroshi Ashida, Tokuju Okano, Tamako Iida, Poramed Onsoi, Chihiro Sasakawa, Toshihiko Suzuki   +5 more
doaj   +1 more source

Q fever is an old and neglected zoonotic disease in Kenya: a systematic review

BMC Public Health, 2016
Background Q fever is a neglected zoonosis caused by the bacterium Coxiella burnetii. The knowledge of the epidemiology of Q fever in Kenya is limited with no attention to control and prevention programs.
J. Njeru, K. Henning, M. W. Pletz, R. Heller, H. Neubauer   +4 more
doaj   +1 more source

Coxiella burnetii Blocks Intracellular Interleukin-17 Signaling in Macrophages [PDF]

, 2018
Coxiella burnetii is an obligate intracellular bacterium and the etiological agent of Q fever. Successful host cell infection requires the Coxiella type IVB secretion system (T4BSS), which translocates bacterial effector proteins across the vacuole ...
Clemente, Tatiana M., Gilk, Stacey D., Justis, Anna V., Mulye, Minal, Nallandhighal, Srinivas, Tran, Tuan M.   +5 more
core   +1 more source