Results 261 to 270 of about 1,163,633 (287)

Mechanical Interactions Impact the Functions of Immune Cells and Their Application in Immunoengineering

Advanced Therapeutics, EarlyView.
This review covers the mechanical forces experienced by immune cells through cell–cell and cell–extracellular matrix interactions and how these forces influence their receptors and functions. These relationships between forces and cellular functions can be exploited using engineering techniques to modify the physical properties of materials for novel ...
Yu‐Chang Chen, Nghi M. Tran, Kyle H. Vining   +2 more
wiley   +1 more source

Bacteriophages as an alternative strategy for the treatment of drug resistant bacterial infections: Current approaches and future perspectives. [PDF]

Cell Surf
Girma A.
europepmc   +1 more source

Rewiring Neuroimmunity: Nanoplatform Innovations for CNS Disease Therapy

Advanced Therapeutics, EarlyView.
This review explores emerging nanoplatform strategies designed to modulate neuroimmune responses for treating central nervous system (CNS) disorders. It examines structural and microenvironmental barriers, advances in multifunctional and targeted nanotechnologies, and highlights clinical progress and translational challenges, offering insights into the
Muhammad Usman Akbar, Weiwei Guo, Xin Shen, Yimeng Fang, Yilin Liu, Peng‐Yuan Wang, Roey Elnathan, Yaping Chen   +7 more
wiley   +1 more source

Biomaterials-based phototherapy for bacterial infections. [PDF]

Front Pharmacol
Wu G, Xu Z, Yu Y, Zhang M, Wang S, Duan S, Liu X.   +6 more
europepmc   +1 more source

Loss of NR2F6 Protects from Salmonella Typhimurium Infection

Advanced Science, EarlyView.
Loss of nuclear receptor NR2F6 reduces tissue‐resident macrophage populations. Nr2f6‐deficient mice are protected from weight loss and bacterial load during infection with Salmonella Typhimurium. Pro‐inflammatory cytokines and iron levels are altered in infected Nr2f6‐deficient mice.
Johannes Woelk, Christa Pfeifhofer‐Obermair, Julia Benz, Natascha Brigo, Milena Bamberger, Alexeja Kleiter, Martin Hermann, Guenter Weiss, Natascha Hermann‐Kleiter   +8 more
wiley   +1 more source

ENaC is a host susceptibility factor to bacterial infections in cystic fibrosis context. [PDF]

Commun Biol
Touré H, Durand N, Orgeur M, Galindo LA, Girard-Misguich F, Guénal I, Herrmann JL, Szuplewski S.   +7 more
europepmc   +1 more source

Multivariate Screening and Automated Clustering of Macrophage Immunoreactome to Nanoparticles and Photothermal Therapy

Advanced Science, EarlyView.
Predicting immune responses to treatments, including nanomedicines, with high throughput test is challenging due to the immunoreactome's complexity and plasticity. A predictive screening platform integrating pathway activation and gene profiling in macrophages has been developed as a versatile tool for designing effective immunotherapies.
Sonia Becharef, Léa Jabbour, Nassima Bekaddour, Giulio Avveduto, Nathalie Luciani, Gautier Laurent, Rana Bazzi, Edouard Alphandery, Stéphane Roux, Amanda K. A. Silva, Kelly Aubertin, Jean‐Philippe Herbeuval, Florence Gazeau   +12 more
wiley   +1 more source

Harnessing Plant-Based Nanoparticles for Targeted Therapy: A Green Approach to Cancer and Bacterial Infections. [PDF]

Int J Mol Sci
Rîmbu MC, Cord D, Savin M, Grigoroiu A, Mihăilă MA, Gălățanu ML, Ordeanu V, Panțuroiu M, Țucureanu V, Mihalache I, Brîncoveanu O, Boldeiu A, Anăstăsoaie V, Manea CE, Sandulovici RC, Chirilă M, Turcu-Știolică A, Amzoiu E, Peteu VE, Tănase C, Firtat B, Mihăilescu CM.   +21 more
europepmc   +1 more source

Self‐Adjusting Engineered Probiotic for Targeted Tumor Colonization and Local Therapeutics Delivery

Advanced Science, EarlyView.
Zou et al. developed an engineered strain of Escherichia coli Nissle 1917 with precise targeting abilities for colonization and on‐demand payload release. The engineered probiotic survives and embolizes tumors only in the presence of more than 5 mM L‐lactate. Furthermore, the introduction of an α‐hemolysin circuit enhances its anti‐tumor effect.
Zhen‐Ping Zou, Xin‐Ge Wang, Xuan‐Ren Shi, Shu‐Ting Sun, Jing Mi, Xiao‐Peng Zhang, Bin‐Cheng Yin, Ying Zhou, Bang‐Ce Ye   +8 more
wiley   +1 more source

Multi-strain phage induced clearance of bacterial infections. [PDF]

PLoS Comput Biol
Marchi J, Minh CNN, Debarbieux L, Weitz JS.   +3 more
europepmc   +1 more source