Results 41 to 50 of about 2,424,208 (316)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

The missing thread of One Health efforts: improper drug disposal as an overlooked driver of antimicrobial resistance

mSphere
With gradual recognition of the components and the stakeholders, “One Health approach” became a global strategy for mitigating antimicrobial resistance (AMR).
Sandip Mukhopadhyay, Falguni Debnath, Debjit Chakraborty   +2 more
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Exploring the burden of diarrheal disease and associated WASH practices in rural West Bengal, India: an explanatory sequential mixed-method approach

Scientific Reports
Diarrheal diseases continue to be a major public health concern in low- and middle-income countries, where insufficient water, sanitation, and hygiene (WASH) practices lead to a substantial community burden.
Suman Kanungo, Shubhajit Pahari, Aritra Paul, Rounik Talukdar, Sombuddha Biswas, Sougata Chatterjee, Diplina Barman, Debjit Chakraborty, Pramit Ghosh, Bipul Chandra Karmakar, Atreyi Chakrabarti, Swati Pramanick, Asish Kumar Mukhopadhyay, Ranjan Kumar Nandy, Alok Kumar Deb, Falguni Debnath, Shanta Dutta, Debasis Roy, Mukti Sadhan Maiti, Dipankar Maji   +19 more
doaj   +1 more source

Third-generation cephalosporin-induced L-form transition in Shigella sonnei reveals a virulence-survival trade-off underlying persistent infection

Microbiology Spectrum
Shigellosis remains a major global health burden, and the increasing prevalence of multidrug-resistant (MDR) Shigella strains is complicating effective antibiotic therapy. Bacteria may survive antibiotics by transitioning into cell wall-deficient L-forms,
Sanjib Das, Arindam Mukherjee, Prolay Halder, Soumalya Banerjee, Supriya Mandal, Nivedita Roy, Ashis Debnath, Sreejani Banerjee, Manjistha Manna, Upama Mandal, Jiro Mitobe, Jeffrey H. Withey, Asish Kumar Mukhopadhyay, Santasabuj Das, Debaki Ranjan Howlader, Hemanta Koley   +15 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Mycotic and Bacterial Infections

Clinics in Colon and Rectal Surgery, 2019
AbstractThis article reviews the salient clinical features, evaluation, and treatment of mycotic and bacterial infections of the perianal and contiguous zones of the human body.
Phillip M, Duldulao, Adrián E, Ortega, Xavier, Delgadillo   +2 more
openaire   +3 more sources

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Impact of mandatory vaccination against serogroup C meningococci in targeted and non-targeted populations in France

npj Vaccines, 2022
Since January 2018, mandatory vaccination against meningococci serogroup C has been implemented in France for children
Samy Taha, Muhamed-Kheir Taha, Ala-Eddine Deghmane   +2 more
doaj   +1 more source