Results 21 to 30 of about 861,479 (259)

Vibrio parahaemolyticus Senses Intracellular K⁺ To Translocate Type III Secretion System 2 Effectors Effectively

mBio, 2018
Many Gram-negative bacterial symbionts and pathogens employ a type III secretion system (T3SS) to live in contact with eukaryotic cells. Because T3SSs inject bacterial proteins (effectors) directly into host cells, the switching of secretory substrates ...
Sarunporn Tandhavanant, Shigeaki Matsuda, Hirotaka Hiyoshi, Tetsuya Iida, Toshio Kodama   +4 more
doaj   +1 more source

Phylogenomic Analysis of Campylobacter fetus Reveals a Clonal Structure of Insertion Element ISCfe1 Positive Genomes

Frontiers in Microbiology, 2020
Subspecies of the species Campylobacter fetus are associated with specific host niches including mammals and reptiles. Campylobacter fetus subsp. fetus is a zoonotic pathogen infecting humans.
Mostafa Y. Abdel-Glil, Mostafa Y. Abdel-Glil, Helmut Hotzel, Herbert Tomaso, Jörg Linde   +4 more
doaj   +1 more source

First record of the human infection of Brucella melitensis in Kyrgyzstan: evidence from whole-genome sequencing-based analysis

Infectious Diseases of Poverty, 2022
Background Brucellosis, a zoonosis mainly transmitted by consumption of unpasteurized dairy products as well as direct contact with infected animals, is endemic in Kyrgyzstan.
Kalysbek Kydyshov, Nurbolot Usenbaev, Stalbek Berdiev, Aigul Dzhaparova, Aziza Abidova, Nuraiym Kebekbaeva, Murat Abdyraev, Gamal Wareth, Hanka Brangsch, Falk Melzer, Heinrich Neubauer, Mathias W. Pletz   +11 more
doaj   +1 more source

Immunogenicity and safety among laboratory workers vaccinated with Bexsero® vaccine

Human Vaccines & Immunotherapeutics, 2017
Neisseria meningitidis serogroup B is the most prevalent cause of invasive meningococcal disease in Europe and members of laboratories working on meningococci are at risk due to frequent handling.
Eva Hong, Aude Terrade, Muhamed-Kheir Taha   +2 more
doaj   +1 more source

Characterization of Unusual Serogroups of Neisseria meningitidis

Microorganisms
Most cases of invasive meningococcal disease (IMD) in Europe are caused by isolates of the Neisseria meningitidis serogroups B, C, W, and Y. We aimed to explore cases caused by other unusual serogroups.
Samy Taha, Giulia Fantoni, Eva Hong, Aude Terrade, Oumar Doucoure, Ala-Eddine Deghmane, Muhamed-Kheir Taha   +6 more
doaj   +1 more source

FKBPs in bacterial infections

Biochimica et Biophysica Acta (BBA) - General Subjects, 2015
FK506-binding proteins (FKBPs) contain a domain with peptidyl-prolyl-cis/trans-isomerase (PPIase) activity and bind the immunosuppressive drugs FK506 and rapamycin. FKBPs belong to the immunophilin family and are found in eukaryotes and bacteria.In this review we describe two major groups of bacterial virulence-associated FKBPs, the trigger factor and ...
Unal, Can M., Steinert, Michael
openaire   +4 more sources

Impact of mandatory vaccination against serogroup C meningococci in targeted and non-targeted populations in France

npj Vaccines, 2022
Since January 2018, mandatory vaccination against meningococci serogroup C has been implemented in France for children
Samy Taha, Muhamed-Kheir Taha, Ala-Eddine Deghmane   +2 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Systematic review of brucellosis in Kenya: disease frequency in humans and animals and risk factors for human infection

BMC Public Health, 2016
Background Brucellosis is a debilitating zoonotic disease affecting humans and animals. A comprehensive, evidence-based assessment of literature and officially available data on animal and human brucellosis for Kenya are missing.
J. Njeru, G. Wareth, F. Melzer, K. Henning, M. W. Pletz, R. Heller, H. Neubauer   +6 more
doaj   +1 more source

WGS based analysis of acquired antimicrobial resistance in human and non-human Acinetobacter baumannii isolates from a German perspective

BMC Microbiology, 2021
Background Acinetobacter baumannii ability to develop and acquire resistance makes it one of the most critical nosocomial pathogens globally. Whole-genome sequencing (WGS) was applied to identify the acquired or mutational variants of antimicrobial ...
Gamal Wareth, Christian Brandt, Lisa D. Sprague, Heinrich Neubauer, Mathias W. Pletz   +4 more
doaj   +1 more source