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Infectious bronchitis virus (IBV) represents a major threat to poultry production, with current control strategies offering limited protection. In this study, we demonstrate gut microbiome is a critical determinant of IBV resistance using fecal microbiota transplantation.
Ouyang Peng +22 more
wiley +1 more source
Our study employed an integrated lipidomics and metabolomics approach to elucidate Helicobacter pylori‐driven metabolic perturbations along the gut–brain axis. H. pylori infection was established in gastric epithelial (AGS) cells, and the resulting conditioned media (secretome) was collected and exposed to neuronal (IMR‐32) cells.
Meenakshi Kandpal +4 more
wiley +1 more source
Membrane vesicle-mediated bacterial communication
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Bacterial membrane vesicles for vaccine applications
Advanced Drug Delivery Reviews, 2022Vaccines have been highly successful in the management of many diseases. However, there are still numerous illnesses, both infectious and noncommunicable, for which there are no clinically approved vaccine formulations. While there are unique difficulties that must be overcome in the case of each specific disease, there are also a number of common ...
Nishta, Krishnan +5 more
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Pathogenesis Mediated by Bacterial Membrane Vesicles
2021The release of extracellular vesicles (EVs) is a process conserved across the three domains of life. Amongst prokaryotes, EVs produced by Gram-negative bacteria, termed outer membrane vesicles (OMVs), were identified more than 50 years ago and a wealth of literature exists regarding their biogenesis, composition and functions. OMVs have been implicated
William J, Gilmore +2 more
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Bacterial membrane vesicles in inflammatory bowel disease
Life Sciences, 2022Inflammatory bowel disease (IBD) is characterized by chronic intestinal inflammation with no cure. The intestine is fundamental in controlling human health. Disruption of the microbial ecosystem in the intestine is considered an important cause of IBD.
Qichen, Shen +4 more
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Composition and functions of bacterial membrane vesicles
Nature Reviews Microbiology, 2023Extracellular vesicles are produced by species across all domains of life, suggesting that vesiculation represents a fundamental principle of living matter. In Gram-negative bacteria, membrane vesicles (MVs) can originate either from blebs of the outer membrane or from endolysin-triggered explosive cell lysis, which is often induced by genotoxic stress.
Toyofuku, Masanori +3 more
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Roles of bacterial membrane vesicles
Archives of Microbiology, 2014Outer membrane vesicles (OMVs) are released from the outer membrane of Gram-negative bacteria. Moreover, Gram-positive bacteria also produce membrane-derived vesicles. As OMVs transport several bacterial components, especially from the cell envelope, their interaction with the host cell, with other bacteria or as immunogens, have been studied intensely.
Eric Daniel, Avila-Calderón +6 more
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