Results 101 to 110 of about 90,276 (274)

Beyond the Kidney and Lung: Cutaneous and Mucosal Clues to Human Hantavirus Disease

International Journal of Dermatology, EarlyView.
Rodent exposure and aerosolized excreta can lead to hantavirus infection with systemic endothelial injury and capillary leak, resulting in thrombocytopenia and syndromes such as HPS/HCPS and HFRS/NE. Early dermatologic and mucosal findings, including flushing, conjunctival injection, petechiae/purpura, and mucosal bleeding, may provide important clues ...
Giuseppe Gallo, Pietro Quaglino, Simone Ribero   +2 more
wiley   +1 more source

Bacterial meningitis: current therapy and possible future treatment options

, 2011
Despite targeted therapy, case-fatality rates and neurologic sequelae of bacterial meningitis remain unacceptably high. The poor outcome is mainly due to secondary systemic and intracranial complications. These complications seem to be both a consequence
Grandgirard, Denis, Uwe Koedel, Klein, Matthias, Stephen Leib, Leib, Stephen, Woehrl, Bianca, Denis Grandgirard, Koedel, Uwe, Bianca Woehrl, Matthias Klein   +9 more
core   +1 more source

Vectors and Vector‐Borne Diseases: Biology, Epidemiology and Integrated Control Strategies

Journal of Applied Entomology, EarlyView.
ABSTRACT Vector‐Borne Diseases (VBDs), transmitted by arthropods such as mosquitoes, ticks, fleas and sandflies, represent a significant threat to global health. These diseases can be caused by a variety of pathogens, including bacteria, viruses, protozoa, and helminths.
Roberta Rinaldi, Carmen Scieuzo, Federica De Stefano, Luca Masucci, Patrizia Falabella   +4 more
wiley   +1 more source

Genotypic diversity is associated with clinical outcome and phenotype in cryptococcal meningitis across Southern Africa [PDF]

, 2015
This work was supported by Wellcome Trust (UK) (www.wellcome.ac.uk) awards to TB (WT069991), GM (WT098316), and JNJ (WT081794); Medical Research Council (MRC UK) (www.mrc.ac.uk) awards to MCF (K000373/1), RCM (G0601171), TSH (G1002327); European Research
Fisher, Matthew C, Matthew C Fisher, Matthew C. Fisher (129755), Angela Loyse (292490), Meintjes, Graeme, Fisher, Matthew C., Emma J. Robertson (760738), Sabiiti, Wilber, O'Hanlon, SJ, O'Hanlon, Simon J, Joseph N Jarvis, Tihana Bicanic (718812), Thomas S. Harrison (222993), Fisher, MC, Karen M Fuentes-Cabrejo, Fuentes-Cabrejo, KM, Fuentes-Cabrejo, Karen M, Angela Loyse, Fisher, M, Harrison, Thomas S, Harrison, TS, Robertson, EJ, Simon J. O’Hanlon (760740), Loyse, Angela, Meintjes, G, Simon J O'Hanlon, Robin C May, Jarvis, Joseph N, Emma J Robertson, Wilber Sabiiti (170648), Thomas S Harrison, Mathew A. Beale (663616), Wilber Sabiiti, Robertson, Emma J, Joseph N. Jarvis (435279), Robertson, Emma J., Jarvis, JN, May, Robin C, Mathew A Beale, Karen M. Fuentes-Cabrejo (760739), Graeme Meintjes (221054), Beale, Mathew A, Tihana Bicanic, Sabiiti, W, Bicanic, T, May, RC, Loyse, A, May, Robin C; id_orcid, Bicanic, Tihana, Graeme Meintjes, Beale, MA, Robin C. May (170650)   +51 more
core   +1 more source

Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases

Journal of Periodontal Research, EarlyView.
This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini, George Hajishengallis, Mike Curtis, Giacomo Baima   +3 more
wiley   +1 more source

Incorporating the Competencies of Evidence‐Based Veterinary Medicine Focused on Pharmacotherapeutics Into Clinical Rotations for Small Animal Dermatology and Food Animal Medicine and Surgery at a Veterinary Medical Teaching Hospital in the US

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Building the skills and knowledge necessary to practice evidence‐based veterinary medicine (EBVM) should occur throughout the veterinary curriculum. Operationalizing EBVM includes asking a clinical question in PICO format, searching the biomedical literature for evidence, critically appraising the evidence, and applying the evidence to make a ...
Virginia R. Fajt, Adam P. Patterson, Dusty Nagy, Jennifer Schleining, Kevin Washburn   +4 more
wiley   +1 more source

Pharmacokinetics of Long‐Acting Ampicillin and Its Impact on the Gut Microbiome and Resistome in Rhesus Macaques (Macaca mulatta)

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Injectable antimicrobials with documented prolonged dosing intervals (> 48 h) for use in rhesus macaques are sparse. The objective of our study was to assess the pharmacokinetics, urine excretion, and effects on gut microbiome and resistome of intramuscular administered long‐acting formulation of ampicillin (Albipen LA) in macaques.
Annemiek Maaskant, Ingeborg M. van Geijlswijk, Mathias Devreese, Marc Cherlet, Leo F. van Geest, Jaap A. Wagenaar, Jan A. M. Langermans, Aldert L. Zomer, Jaco Bakker, Ronette Gehring   +9 more
wiley   +1 more source

Bacterial Meningitis

, 2016
Bacterial meningitis is a bacterial infection causing inflammation of the meninges, the lining around the brain and spinal cord. It is important for emergency physicians to recognize potential bacterial meningitis early.
Mary P. Chang
core   +1 more source

Bacterial Meningitis in Childhood

, 2011
A wide variety of pathogens cause childhood meningitis and clinical features and ­outcomes vary according to the organism. Bacterial meningitis caused by Neisseria meningitidis, Streptococcus pneumoniae and Haemophilus influenzae type b (Hib) is of particular importance as it has a high mortality and morbidity, has been relatively common and is ...
Sadarangani, M, Pollard, A
openaire   +3 more sources

Photodynamic inactivation increases cell death rate on persistent Staphylococcus aureus

Photochemistry and Photobiology, EarlyView.
Persistent bacteria have the ability to survive extended periods of antibiotic stress by entering a metabolically dormant state. This study investigated persistence formation in two S. aureus strains and evaluated the effects of PDI using curcumin. Post‐PDI time‐kill assays conducted after metabolic recovery showed a higher rate of bacterial death ...
Maria Vitória Silva Pereira, Bruna Carolina Corrêa, Vanderlei Salvador Bagnato, Kate Cristina Blanco   +3 more
wiley   +1 more source