Results 101 to 110 of about 966,194 (282)

Vaccinations During Pregnancy Protect the Mother–Infant Dyad and Are Generally Safe

Acta Paediatrica, EarlyView.
ABSTRACT Aim Vaccination in pregnancy has a critical impact on mothers, foetuses and infants. The aim of this paper was to summarise key points presented by experts attending the 12th Maria Delivoria‐Papadopoulos Perinatal Symposium in March 2025 and further expand and update them.
Ariadne Malamitsi‐Puchner, Despina D. Briana, Gian Carlo Di Renzo   +2 more
wiley   +1 more source

`Eschericha coli' K1 interactions with human brain microvascular endothelial cells, a primary step in the development of neonatal meningitis [PDF]

Escherichia coli (E. coli) Kl is one of the commonest Gram negative bacteria causing neonatal bacterial meningitis in both developed and developing countries. Haematogenous spread is a key step in E.
Loh, Lip Nam
core   +1 more source

Bacterial meningitis: current therapy and possible future treatment options [PDF]

, 2011
Despite targeted therapy, case-fatality rates and neurologic sequelae of bacterial meningitis remain unacceptably high. The poor outcome is mainly due to secondary systemic and intracranial complications. These complications seem to be both a consequence
Grandgirard, Denis, Uwe Koedel, Klein, Matthias, Stephen Leib, Leib, Stephen, Woehrl, Bianca, Denis Grandgirard, Koedel, Uwe, Bianca Woehrl, Matthias Klein   +9 more
core   +1 more source

A Global Perspective of Childhood Vaccinations: Past, Present, and Future—From Smallpox to mRNA

Acta Paediatrica, EarlyView.
ABSTRACT Childhood immunisation is one of the most successful public health interventions in history, preventing millions of deaths and substantially reducing global child mortality. This mini‐review summarises the historical development of childhood vaccines, the role of global coordination in expanding immunisation coverage, and the innovations that ...
Tobias Alfvén, Tania Reza, Alieu Sowe
wiley   +1 more source

Antimicrobial Resistance in Children With Bloodstream Infections: A Population‐Based Study in Stockholm, Sweden

Acta Paediatrica, EarlyView.
ABSTRACT Aim We retrospectively evaluated trends in antimicrobial resistance (AMR) in paediatric bloodstream infections and assessed changes in antimicrobial prescription patterns over a 20‐year period. Methods We analysed positive blood cultures from children admitted with suspected serious infection between 1998 and 2018.
Joachim Luthander, Rutger Bennet, Per Nydert, Margareta Eriksson, Christian G. Giske, Anna Nilsson   +5 more
wiley   +1 more source

Guidelines for the early clinical and public health management of bacterial meningitis (including meningococcal disease)

, 2012
Bacterial meningitis or septicaemia is a serious condition with high morbidity and significant mortality. Individuals with this disease can present in the community and deteriorate rapidly prior to admission to hospital.
Bacterial Meningitis Sub-Committee of the Scientific Advisory Committee, HPSC
core  

Early diagnosis model for meningitis supports public health decision making.

, 2011
OBJECTIVE: To develop a predictive model for rapid differential diagnosis of meningitis and meningococcal septicaemia to support public health decisions on chemoprophylaxis for contacts.
Ejidokun, Oluwatoyin O, Meltzer, Margie, Neville Q. Verlander, Fraser, Graham, Meltzer, M, Oluwatoyin O. Ejidokun, Rehman, Yasmin, Verlander, Neville Q, Ninis, Nelly, Margie Meltzer, Nelly Ninis, Muir, Peter, Fraser, G, Verlander, NQ, Rehman, Y, Close, RM, James M. Stuart, Graham Fraser, Peter Muir, Muir, P, Stuart, James M, Stuart, JM, Rebecca M. Close, Yasmin Rehman, Close, Rebecca M, Ejidokun, OO   +25 more
core   +1 more source

Copy number variation analysis of cerebrospinal fluid metagenomic next‐generation sequencing data in assisting the diagnosis of pediatric brain tumors

Pediatric Investigation, EarlyView.
Changhong Ren, Xiuwei Zhuo, Xinying Yang, Xingfeng Yao, Shuai Gong, Hui Xiong, Fang Fang, Weihua Zhang   +7 more
wiley   +1 more source

Clinical Features and Predictors of Hospital Stay in Paediatric Epstein–Barr Virus Infectious Mononucleosis: A Multicentre Cohort Study

Acta Paediatrica, EarlyView.
ABSTRACT Aim To describe age‐specific clinical features and identify predictors of length of hospital stay in children and adolescents with primary Epstein–Barr virus (EBV) infectious mononucleosis (IM). Methods This multicentre retrospective cohort study included all children and adolescents aged 0–17 years with a verified primary EBV infection in the
Lasse H. Nyhegn, Sara Yde Steffensen, Sabine Frølich Maarbjerg, Luise Borch, Marianne Kragh Thomsen, Mette Holm   +5 more
wiley   +1 more source

Serum procalcitonin in Egyptian patients with acute meningitis and a negative direct cerebrospinal fluid examination

Journal of Infection and Public Health, 2014
Summary: Background: To reduce the morbidity and mortality related to bacterial meningitis, it is important to discriminate bacterial meningitis from aseptic meningitis during the acute phase of the disease, when the clinical symptoms are often similar.
Nadia A. Abdelkader, Waheed A. Mahmoud, Sally Mohamed Saber   +2 more
doaj   +1 more source