Results 121 to 130 of about 90,276 (274)

Maternal, childhood and adolescent influences on Leydig cell functional capacity and circulating INSL3 concentration in young adults: Importance of childhood infections and body mass index

Andrology, Volume 14, Issue 5, Page 1172-1182, July 2026.
Abstract Background The constitutive Leydig cell hormone insulin‐like peptide 3 (INSL3) is considered a good estimate of the adult Leydig cell functional capacity and appears to remain relatively consistent throughout adult male life, only gradually declining into old age.
Richard Ivell, Bilal Tulumcu, Waleed Alhujaili, Ravinder Anand‐Ivell   +3 more
wiley   +1 more source

Corrigendum to “Phylogenetic relationships and regional spread of meningococcal strains in the meningitis belt, 2011–2016” EBioMedicine 41 (2019) 488–496

EBioMedicine, 2020
Nadav Topaz, Dominique A. Caugant, Muhamed-Kheir Taha, Ola Brønstad Brynildsrud, Nadia Debech, Eva Hong, Ala-Eddine Deghmane, Rasmata Ouédraogo, Sani Ousmane, Kadidja Gamougame, Berthe-Marie Njanpop-Lafourcade, Seydou Diarra, LeAnne M. Fox, Xin Wang   +13 more
doaj   +1 more source

Estimation of serum and CSF lactate as a diagnostic and prognostic marker of bacterial and aseptic meningitis in adults: experience from a tertiary care center

MGM Journal of Medical Sciences
Background: Data on the utility of cerebrospinal fluid (CSF) lactate and serum lactate as prognostic markers for bacterial and viral meningitis remain scarce in the Indian setting.
Hasim Reza, Soumyasil Das, Debasish Gond, Linkon Biswas, Subrata Kumar Pal   +4 more
doaj   +1 more source

Parental Socio‐Economic Factors and the Risk of Invasive Bacterial Infections in Children: A Register‐Based Finnish Study

Acta Paediatrica, Volume 115, Issue 7, Page 1487-1495, July 2026.
ABSTRACT Aim Little is known about how socio‐economic factors influence severe childhood bacterial infections. We explored whether parental socio‐economic status correlates with the risk of invasive bacterial infections in the offspring. Methods Data on children < 16 years with community‐acquired blood or cerebrospinal fluid culture–positive bacterial ...
Kyrönlahti Anniina, Hermunen Teemu, Nieminen Tea, Koivisto Karoliina, Rantanen Matti, Saxén Harri, Madanat‐Harjuoja Laura   +6 more
wiley   +1 more source

Determinants of timely management of acute bacterial meningitis in the ED

, 2013
PURPOSE: The purpose was to study the emergency management of patients with suspected meningitis to identify potential areas for improvement. METHODS: All patients who underwent cerebrospinal fluid puncture at the emergency department of the University ...
Lindner, Gregor, Exadaktylos, Aristomenis K., Täuber, Martin G., Schuh, Sabine, Mühlemann, Kathrin   +4 more
core   +1 more source

Effects of Biological Sex and Age on Cerebrospinal Fluid Markers—A Retrospective Observational Study

Annals of Clinical and Translational Neurology, Volume 13, Issue 6, Page 1222-1235, June 2026.
ABSTRACT Objective Cerebrospinal fluid (CSF) analysis is a key diagnostic tool for neurological diseases. To date, only a few studies have investigated in larger cohorts the effect of age and biological sex on diagnostic markers extracted from CSF. Methods For this retrospective observational study, 4163 CSF findings (2012–2020) were evaluated.
Isabel‐Sophie Hafer, Simon Faissner, Ralf Gold, Aiden Haghikia   +3 more
wiley   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, Volume 92, Issue 6, Page 1787-1808, June 2026.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source

Therapy of community-acquired acute bacterial meningitis: the clock is running

, 2009
Despite antibiotic therapy and supportive intensive medical care, bacterial meningitis remains a disease with high mortality and morbidity. Rapid recognition of symptoms is crucial to direct physicians quickly towards appropriate diagnostic measures and,
Leib, Stephen L., Pfister, H W, Klein, M, Koedel, U   +3 more
core   +1 more source

Assessing transporter‐mediated rifampin–linezolid interaction using physiologically‐based pharmacokinetic modelling

British Journal of Clinical Pharmacology, Volume 92, Issue 6, Page 1845-1856, June 2026.
Abstract Aims The study aims to develop a physiologically‐based pharmacokinetic (PBPK) model to quantitatively evaluate the role of ATP‐binding cassette sub‐family B member 1 (ABCB1) and ATP‐binding cassette super‐family G member 2 (ABCG2) in the drug–drug interaction (DDI) between rifampin and linezolid and to predict the impact of high‐dose rifampin ...
Hoang Dat Nguyen, Vinh Hoa Pham, Richard M. Hoglund, Joel Tarning, Junjie Ding   +4 more
wiley   +1 more source

The evolving therapeutic landscape of spinal muscular atrophy – A scoping review of investigational agents, emerging delivery technologies and strategic innovations

British Journal of Clinical Pharmacology, Volume 92, Issue 6, Page 1552-1566, June 2026.
Spinal muscular atrophy (SMA) is a severe neuromuscular disease with emerging therapeutic complexity. This review aims to systematically map the global pipeline of investigational treatments for SMA. Using ClinicalTrials.gov and complementary international registries, we identified 21 planned or ongoing interventional trials from 2020 to 2025 targeting
Andrej Belančić, Patrick Eustaquio, Elvira Meni Maria Gkrinia, Ivana Stević, Eugen Javor, Yun Wah Lam, Slobodan Janković, Dinko Vitezić   +7 more
wiley   +1 more source