Results 81 to 90 of about 1,141,248 (239)

Surface hydrophilicity promotes bacterial twitching motility

mSphere
Twitching motility is a form of bacterial surface translocation powered by the type IV pilus (T4P). It is frequently analyzed by interstitial colony expansion between agar and the polystyrene surfaces of petri dishes.
Megan T. O'Hara, Tori M. Shimozono, Keane J. Dye, David Harris, Zhaomin Yang   +4 more
doaj   +1 more source

Differential Gene Expression of Three Mastitis-Causing Escherichia coli Strains Grown under Planktonic, Swimming, and Swarming Culture Conditions

mSystems, 2016
Bacterial motility is thought to play an important role in virulence. We have previously shown that proficient bacterial swimming and swarming in vitro is correlated with the persistent intramammary infection phenotype observed in cattle. However, little
John D. Lippolis, Brian W. Brunelle, Timothy A. Reinhardt, Randy E. Sacco, Tyler C. Thacker, Torey P. Looft, Thomas A. Casey   +6 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Barriers to bacterial motility on unsaturated surfaces [PDF]

, 2013
Our knowledge of the spatial organization and spatial dynamics of microbial populations in soil at a scale close to that of the microorganisms is scarce.
Dechesne, Arnaud, Smets, Barth F.
core  

Genome sequence of the pattern forming Paenibacillus vortex bacterium reveals potential for thriving in complex environments [PDF]

, 2010
Background The pattern-forming bacterium Paenibacillus vortex is notable for its advanced social behavior, which is reflected in development of colonies with highly intricate architectures.
Colin Ingham, Lancet, D., Roth Dalit, Bransburg-Zabary Sharron, Alexandra Sirota-Madi, Ingham, C., Nikolaev, V., Sirota-Madi Alexandra, Gutnick, D.L., Yael Helman, Hagi, E., Ben-Jacob, E., Vladimir Galatenko, Olender, T., Nikolaev Vladimir, David L Gutnick, Eshel Ben-Jacob, Brainis, I., Bransburg-Zabary, S., Brodsky Leonid, Tsviya Olender, Sharron Bransburg-Zabary, Gutnick David L, Dena Leshkowitz, Ina Brainis, Roth, D., Olender Tsviya, Brodsky, L., Raja C Mugasimangalam, Ben-Jacob Eshel, Leshkowitz Dena, Mugasimangalam, R.C., Helman, Y., Ingham Colin, Sirota-Madi, A., Hagi Efrat, Leonid Brodsky, Helman Yael, Brainis Ina, Dalit Roth, Doron Lancet, Galatenko Vladimir, Mugasimangalam Raja C, Leshkowitz, D., Galatenko, V., Lancet Doron, Efrat Hagi, Vladimir Nikolaev   +47 more
core   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

RABiTPy: an open-source Python software for rapid, AI-powered bacterial tracking and analysis

BMC Bioinformatics
Bacterial tracking is crucial for understanding the mechanisms governing motility, chemotaxis, cell division, biofilm formation, and pathogenesis. Although modern microscopy and computing have enabled the collection of large datasets, many existing tools
Samyabrata Sen, Indraneel Vairagare, Jitendrapuri Gosai, Abhishek Shrivastava   +3 more
doaj   +1 more source

Helicobacter pylori FlhB function: the F1hB C-terminal homologue HP1575 acts as a "Spare part" to permit flagellar export when the HP0770 FlhB(CC) domain is deleted [PDF]

, 2006
In Helicobacterpylori 26695, a gene annotated HP1575 encodes a putative protein of unknown function which shows significant similarity to part of the C-terminal domain of the flagellar export protein FlhB.
K. J. Evans, N. Doherty, P. M. Sharp, R. E. Sockett, K. R. Hardie, Hardie, Kim R., Winzer, Klaus, K. Winzer, Sharp, Paul M., M. E. Wand, Wand, Matthew E., Evans, Katy J., Doherty, Neil, Sockett, R. Elizabeth   +13 more
core   +1 more source