Results 71 to 80 of about 1,141,248 (239)

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Ecological relevance of flagellar motility in soil bacterial communities

Flagellar motility is a key bacterial trait as it allows bacteria to navigate their immediate surroundings. Not all bacteria are capable of flagellar motility, and the distribution of this trait, its ecological associations, and the life history ...
Strickland, Michael S, Ramoneda, Josep, Fierer, Noah, Bissett, Andrew, Fan, Kunkun, Strickland, Michael S., Lucas, Jane M., Chu, Haiyan   +7 more
core   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

c-di-GMP-mediated pause behavior enables Pseudomonas aeruginosa navigation in porous environments

Applied and Environmental Microbiology
Bacteria frequently encounter porous environments in nature and clinical settings, yet how single-flagellated pathogens navigate such confined spaces remains unclear.
Zihuan Zhang, Rongjing Zhang, Junhua Yuan   +2 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Prolonged CBD Exposure Is Associated with Higher Expression of flgA in Salmonella Typhimurium

Antibiotics
Background/Objectives: Salmonella Typhimurium is a Gram-negative foodborne pathogen that remains a major public-health concern. In this study, we examined whether prolonged exposure to cannabidiol (CBD) was associated with altered flgA expression and ...
Iddrisu Ibrahim, Alexa Mathias, Daron Johnson, Kelci Lawrence, Othreniel Angel Forte, Navitri Chandra Naidu, Latrell Huitt, Nathaniel Ajibola, Junhuan Xu, Robertson K. Boakai, Fortune Akabanda, James Owusu-Kwarteng, Olufemi S. Ajayi, Komal Vig, Joseph Atia Ayariga   +14 more
doaj   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Antimicrobial surfaces based on self-assembled nanoreactors : from block copolymer synthesis to bacterial adhesion study [PDF]

, 2010
The aim of this work is to develop a new strategy for the prevention of biofilm growth. For this purpose, we prepared bioactive surfaces resulting from the surface-immobilization of nanoreactors self-assembled from amphiphilic poly(isobutylene)-block ...
Cottenye, Nicolas
core   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source