Results 111 to 120 of about 111,040 (251)
Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy
Advanced Healthcare Materials, EarlyView.Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima +15 more
wiley +1 more source
Torque-speed relationship of the flagellar motor with dual-stator systems in Pseudomonas aeruginosa
mBioThe single polar flagellar motor in Pseudomonas aeruginosa is equipped with two stator systems, MotAB and MotCD, both driven by H+ ions. The torque-speed relationship for flagellar motors with two stator systems has not been explored previously.
Haolin Wu +4 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.ABSTRACT Sutures are crucial for tissue approximation and wound healing. Besides their strength limits requirement, they often fail to effectively address complications like infection and pain. Inspired by natural silk's “core‐sheath” structure, our suture features a wet‐spun core of n zinc‐fortified silk fibroin fibers (RSF‐Zn2+) after drawing with ...
Yi Peng +11 more
wiley +1 more source
Mechanical limitation of bacterial motility mediated by growing cell chains. [PDF]
Biophys J, 2022 McMahon SG, Melville SB, Chen J.
europepmc +1 more source
Advanced Healthcare Materials, EarlyView.This study investigates the M13 bacteriophage as a biomimetic nanovector capable of crossing in vitro models of the blood–brain barrier. By exploiting peculiar transcellular pathways, M13 avoids lysosomal degradation and preserves its structural integrity and functionality.
Silvia Vercellino +12 more
wiley +1 more source
The stationary phase-specific sRNA FimR2 is a multifunctional regulator of bacterial motility, biofilm formation and virulence. [PDF]
Nucleic Acids Res, 2022 Raad N +3 more
europepmc +1 more source
Advanced Healthcare Materials, EarlyView.Peritoneal carcinomatosis is a hard‐to‐treat spread of abdominal cancers that often returns after therapy. Nanoparticles were developed to retain an immune‐boosting drug in the abdomen. When combined with chemotherapy in mice, this approach eliminated tumors in many cases and prevented recurrence, helping the immune system mount a stronger, longer ...
Vanessa Chan +10 more
wiley +1 more source
Plasmonic Enhancement of Fluorescence and Protein Dynamics in Living Mammalian Cells
Advanced Materials, EarlyView.This study demonstrates plasmonic enhancement of the function of fluorescent voltage sensing proteins (genetically encoded voltage indicators, (GEVIs), QuasAr6) in live mammalian cells. Coupling to plasmonic nanoparticles does not just increase fluorescence, but influences the protein photocycle, creating a hybrid sensor with its response speed to ...
Marco Locarno +16 more
wiley +1 more source
Rapid Bacterial Motility Monitoring Using Inexpensive 3D-Printed OpenFlexure Microscopy Allows Microfluidic Antibiotic Susceptibility Testing. [PDF]
Micromachines (Basel), 2022 Diep TT, Needs SH, Bizley S, Edwards AD.
europepmc +1 more source