Results 61 to 70 of about 111,040 (251)

Saturated long-chain fatty acid-producing bacteria contribute to enhanced colonic motility in rats

open access: yesMicrobiome, 2018
Background The gut microbiota is closely associated with gastrointestinal (GI) motility disorder, but the mechanism(s) by which bacteria interact with and affect host GI motility remains unclear.
Ling Zhao   +16 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Swimming Motility, a Virulence Trait of Ralstonia solanacearum, Is Regulated by FlhDC and the Plant Host Environment

open access: yesMolecular Plant-Microbe Interactions, 2004
Swimming motility allows the bacterial wilt pathogen Ralstonia solanacearum to efficiently invade and colonize host plants. However, the bacteria are essentially nonmotile once inside plant xylem vessels.
Julie Tans-Kersten   +2 more
doaj   +1 more source

Roles for motility in bacterial–host interactions [PDF]

open access: yesMolecular Microbiology, 1997
The ability to move in a directed manner may confer distinct advantages upon host‐adapted prokaryotes. Potential benefits of motility include increased efficiency of nutrient acquisition, avoidance of toxic substances, the ability to translocate to preferred hosts and access optimal colonization sites within them, and dispersal in the environment ...
K M, Ottemann, J F, Miller
openaire   +2 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

c-di-GMP-mediated pause behavior enables Pseudomonas aeruginosa navigation in porous environments

open access: yesApplied and Environmental Microbiology
Bacteria frequently encounter porous environments in nature and clinical settings, yet how single-flagellated pathogens navigate such confined spaces remains unclear.
Zihuan Zhang   +2 more
doaj   +1 more source

Bacterial Motility in Biofilm Under Shear Flow

open access: yesChemical Engineering Transactions, 2022
A key role in bacteria surfaces contamination and biofilm development is played by cell motility and adhesion, that can be heavily dependent on flow conditions.
Daniele Marra   +3 more
doaj   +1 more source

The influence of motility on bacterial accumulation in a microporous channel

open access: yesSoft Matter, 2021
We study the transport of bacteria in a porous media modeled by a square channel containing one cylindrical obstacleviamolecular dynamics simulations coupled to a lattice Boltzmann fluid.
Miru Lee   +4 more
openaire   +6 more sources

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

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