Results 141 to 150 of about 172,115 (282)

Dipiperazine‐Phenyl Derivatives Based on Convergent Molecular Platforms Can Reverse Multidrug Resistance in Gram‐Negative Bacteria by Inhibiting Efflux and Permeabilizing Cell Membranes

Advanced Science, EarlyView.
By integrating a convergent molecular platform strategy, this study designed a novel dual‐target C5 to combat multidrug‐resistant Gram‐negative bacteria. C5 synergistically enhances antibiotic efficacy by inhibiting efflux pumps and increasing bacterial membrane permeability.
Jiale Dong, Ting Guo, Yi Huang, Yangchun Ma, Weijin Chen, Jie Xue, Jun Jiang, Enhui Dong, Yue Kong, Hang Ding, Wenlong Zhang, Shutao Ma   +11 more
wiley   +1 more source

Crystallization and Preliminary X-ray Diffraction Analysis of ScrY, a Specific Bacterial Outer Membrane Porin

, 1993
Doris Forst, Katrin Schülein, Thomas Wacker, Kay Diederichs, W. Kreutz, Roland Benz, Wolfram Welte   +6 more
openalex   +2 more sources

Bacterial Outer Membrane Vesicles Induce a Transcriptional Shift in Arabidopsis Towards Immune System Activation Leading to Suppression of Pathogen Growth in Planta [PDF]

, 2021
Laura Chalupowicz, Gideon Mordukhovich, Nofar Assoline, Leron Katsir, Noa Sela, Ofir Bahar   +5 more
openalex   +1 more source

Bioengineering modification and application of bacterial outer membrane vesicles. [PDF]

Int J Med Sci
Wen Y, Si Y, Jia X, Han Z, Zhou Z, Wu Z, Zheng J.   +6 more
europepmc   +1 more source

TriCON: A Carbon‐Based Triple‐Modal Nanoplatform for Pancreatic Cancer Therapy

Advanced Science, EarlyView.
We developed TriCON, a triple‐modality nanotherapeutic platform, to treat pancreatic ductal adenocarcinoma (PDAC) by synergizing gene editing, chemotherapy, and immunotherapy. TriCON utilizes CRISPR/Cas9 to target the poliovirus receptor (PVR), combined with nano‐encapsulated doxorubicin and checkpoint blockade. This approach achieved significant tumor
Xinyu Peng, Jiaxing Huang, Shengnan Lv, Jian Zhang, Liangliang Zhang, Huan Liu, Yan Liu, Zhen‐An Qiao, Feng Wei, Bao‐Lian Su   +9 more
wiley   +1 more source

Engineering New Immunotherapies against Cancer using Bacterial Outer Membrane Vesicles and Supported by Preclinical Data

, 2022
James E. Galen, Thanh Long Pham
openalex   +2 more sources

The role and mechanism of bacterial outer membrane vesicles in the development of periodontitis. [PDF]

Front Microbiol
Wang H, Sun J, Ma G, You F, Heng BC, Bai Y, Deng X.   +6 more
europepmc   +1 more source

Syntaxin 3B Mediates Light‐Dependent Interactions with STXBP1 and Arrestin 4: Distinct Roles in Rods and Cones

Advanced Science, EarlyView.
The present study investigates a cone‐specific STX3 knockout model, displaying a complete loss of cone function, a later onset reduction in rod function, and photoreceptor cell death. A cone‐specific depletion of STXBP1 and ARR4 could be observed in this model.
Lars Tebbe, Larissa Ikelle, Mustafa S. Makia, Mashal Kakakhel, Muayyad R. Al‐Ubaidi, Muna I. Naash   +5 more
wiley   +1 more source

Control of Gene Expression at a Bacterial Leader RNA, the agn43 Gene Encoding Outer Membrane Protein Ag43 of Escherichia coli [PDF]

, 2014
Anu Wallecha, Heather Oreh, Marjan W. van der Woude, Pieter L. deHaseth   +3 more
openalex   +1 more source

From gatekeepers to mitochondrial mischief: how bacterial outer membrane proteins crash the host cell party. [PDF]

FEMS Microbiol Rev
Osset-Trenor P, Proft M, Pascual-Ahuir A.   +2 more
europepmc   +1 more source